2.6.1.40: (R)-3-amino-2-methylpropionate-pyruvate transaminase

This is an abbreviated version!
For detailed information about (R)-3-amino-2-methylpropionate-pyruvate transaminase, go to the full flat file.

Reaction

Synonyms

aminotransferase, D-3-aminoisobutyrate-pyruvate, beta-aminoisobutyrate-pyruvate aminotransferase, D-3-aminoisobutyrate-pyruvate aminotransferase, D-3-aminoisobutyrate-pyruvate transaminase, D-AIB AT, D-BAIB aminotransferase, EC 2.6.1.61

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.1 Transaminases

                2.6.1.40 (R)-3-amino-2-methylpropionate-pyruvate transaminase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
4	Activating Compound
28	AA Sequence
1	CAS Registry Number
7	Cofactor
3	Disease/ Diagnostics
35	Inhibitors
1	Ki Value [mM]
3	KM Value [mM]
3	Localization
7	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
11	Organism
3	Pathway
4	pH Optimum
1	pH Range
4	Purification (Commentary)
2	Reaction
1	Reaction Type
11	Reference
16	Source Tissue
4	Specific Activity [micromol/min/mg]
5	Storage Stability
49	Substrates and Products (Substrate)
4	Subunits
7	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]

Substrates Products

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Substrates Products on EC 2.6.1.40 - (R)-3-amino-2-methylpropionate-pyruvate transaminase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Substrate/Product Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

(R)-3-amino-2-methylpropanoate + 2-oxo-n-butanoate

2-methyl-3-oxopropanoate + 2-amino-n-butanoate

Rattus norvegicus

-

-

644430

-

-

?

(R)-3-amino-2-methylpropanoate + 2-oxo-n-pentanoate

2-methyl-3-oxopropanoate + norvaline

Rattus norvegicus

-

-

644430

-

-

?

(R)-3-amino-2-methylpropanoate + glyoxylate

2-methyl-3-oxopropanoate + glycine

3 entries

(R)-3-amino-2-methylpropanoate + oxaloacetate

2-methyl-3-oxopropanoate + L-aspartate

2 entries

(R)-3-amino-2-methylpropanoate + pyruvate

2-methyl-3-oxopropanoate + L-alanine

10 entries

(S)-2-aminobutyrate + pyruvate

2-oxobutanoate + L-alanine

Rattus norvegicus

-

-

644431

-

-

?

4-aminobutanoate + pyruvate

succinic semialdehyde + L-alanine

Sus scrofa

-

transamination at 19% the rate of (R)-3-amino-2-methylpropanoate

644428

-

-

?

5-aminolevulinic acid + pyruvate

5-oxolevulinic acid + L-alanine

Rattus norvegicus

-

-

644426, 644430

-

-

?

arginine + pyruvate

2-oxo-5-guanidinovaleric acid + L-alanine

Rattus norvegicus

-

transamination at 40% the rate of (R)-3-amino-2-methylpropanoate

644430

-

-

?

beta-alanine + pyruvate

malonic semialdehyde + L-alanine

3 entries

DL-3-amino-n-butanoate + pyruvate

3-oxobutanoate + L-alanine

Rattus norvegicus

-

-

644430

-

-

?

DL-alpha-ethyl-beta-alanine + pyruvate

2-ethyl-3-oxopropanoate + L-alanine

Sus scrofa

-

transamination at 33% the rate of (R)-3-amino-2-methylpropanoate

644428

-

-

?

glycine + pyruvate

glyoxylate + L-alanine

Rattus norvegicus

-

-

644430

-

-

?

NG,NG'-dimethyl-(S)-arginine + pyruvate

? + L-alanine

Rattus norvegicus

-

-

644426, 644430

-

-

?

additional information

?

-

13 entries

(R)-3-amino-2-methylpropanoate + glyoxylate

2-methyl-3-oxopropanoate + glycine

Rattus norvegicus

-

-

644426, 644428, 644430, 644431

-

-

?

(R)-3-amino-2-methylpropanoate + glyoxylate

2-methyl-3-oxopropanoate + glycine

Rattus norvegicus

-

with 90% efficiency compared to pyruvate

636964

-

-

r

(R)-3-amino-2-methylpropanoate + glyoxylate

2-methyl-3-oxopropanoate + glycine

Sus scrofa

-

with 50% efficiency compared to pyruvate

644428

-

-

?

(R)-3-amino-2-methylpropanoate + oxaloacetate

2-methyl-3-oxopropanoate + L-aspartate

Rattus norvegicus

-

-

644426, 644430

-

-

?

(R)-3-amino-2-methylpropanoate + oxaloacetate

2-methyl-3-oxopropanoate + L-aspartate

Rattus norvegicus

-

with 63% efficiency compared to pyruvate

636964

-

-

r

(R)-3-amino-2-methylpropanoate + pyruvate

2-methyl-3-oxopropanoate + L-alanine

Cavia porcellus

-

best substrate among omega-amino acids, highly specific for D-isomer

644428

-

644428

r

(R)-3-amino-2-methylpropanoate + pyruvate

2-methyl-3-oxopropanoate + L-alanine

Cavia porcellus

-

first step in aminoisobutyrate metabolism

644428

-

644428

?

(R)-3-amino-2-methylpropanoate + pyruvate

2-methyl-3-oxopropanoate + L-alanine

Homo sapiens

-

-

644428

-

644428

?

(R)-3-amino-2-methylpropanoate + pyruvate

2-methyl-3-oxopropanoate + L-alanine

Homo sapiens

-

first step in aminoisobutyrate metabolism

644428

-

644428

?

(R)-3-amino-2-methylpropanoate + pyruvate

2-methyl-3-oxopropanoate + L-alanine

Rattus norvegicus

-

-

644426

-

644426

?

(R)-3-amino-2-methylpropanoate + pyruvate

2-methyl-3-oxopropanoate + L-alanine

Rattus norvegicus

-

-

644430

-

644430

?

(R)-3-amino-2-methylpropanoate + pyruvate

2-methyl-3-oxopropanoate + L-alanine

Rattus norvegicus

-

-

644428

i.e. methylmalonyl semialdehyde

644428

?

(R)-3-amino-2-methylpropanoate + pyruvate

2-methyl-3-oxopropanoate + L-alanine

Rattus norvegicus

-

first step in aminoisobutyrate metabolism

644428

-

644428

?

(R)-3-amino-2-methylpropanoate + pyruvate

2-methyl-3-oxopropanoate + L-alanine

Sus scrofa

-

-

644428

-

644428

?

(R)-3-amino-2-methylpropanoate + pyruvate

2-methyl-3-oxopropanoate + L-alanine

Sus scrofa

-

first step in aminoisobutyrate metabolism

644428

-

644428

?

beta-alanine + pyruvate

malonic semialdehyde + L-alanine

Rattus norvegicus

-

-

644426, 644428, 644430

-

-

?

beta-alanine + pyruvate

malonic semialdehyde + L-alanine

Rattus norvegicus

-

transamination at 66% the rate of (R)-3-amino-2-methylpropanoate

636964

-

-

?

beta-alanine + pyruvate

malonic semialdehyde + L-alanine

Sus scrofa

-

transamination at 66% the rate of (R)-3-amino-2-methylpropanoate

644428

-

-

?

additional information

?

-

Cavia porcellus

-

-

644428

-

-

?

additional information

?

-

Homo sapiens

-

-

644428

-

-

?

additional information

?

-

Rattus norvegicus

-

overview

636964

-

-

?

additional information

?

-

Rattus norvegicus

-

overview

644426

-

-

?

additional information

?

-

Rattus norvegicus

-

overview

644430

-

-

?

additional information

?

-

Rattus norvegicus

-

no substrate: 2-oxoglutarate

636964

-

-

?

additional information

?

-

Rattus norvegicus

-

no substrate: 2-oxoglutarate

644426

-

-

?

additional information

?

-

Rattus norvegicus

-

no substrate: 2-oxoglutarate

644428

-

-

?

additional information

?

-

Rattus norvegicus

-

gamma-aminobutanoate is neither substrate nor inhibitor

636964

-

-

?

additional information

?

-

Rattus norvegicus

-

no substrate: phenylpyruvate

636964

-

-

?

additional information

?

-

Rattus norvegicus

-

no substrate: phenylpyruvate

644426

-

-

?

additional information

?

-

Sus scrofa

-

no substrate: 2-oxoglutarate

644428

-

-

?

additional information

?

-

Sus scrofa

-

no substrate: 5-amino-n-pentanoate, 6-aminohexanoate, DL-3-aminobutyrate, oxaloacetate

644428

-

-

?