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2.6.1.4: glycine transaminase

This is an abbreviated version!
For detailed information about glycine transaminase, go to the full flat file.

Word Map on EC 2.6.1.4

Reaction

glycine
+
2-oxoglutarate
=
glyoxylate
+
L-glutamate

Synonyms

aminotransferase, glycine, AT2, GGT, glutamate-glycine transaminase, glutamate:glyoxylate aminotransferase, glutamic-glycine transaminase, glutamic-glyoxylic transaminase, GlyAT, glycine aminotransferase, glyoxylate-glutamate aminotransferase, glyoxylate-glutamic transaminase, GPT, L-glutamate:glyoxylate aminotransferase, Os07g0108300, PSAT1

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.4 glycine transaminase

Inhibitors

Inhibitors on EC 2.6.1.4 - glycine transaminase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3-chloro-L-alanine
-
-
Aminooxyacetate
-
-
ammonium chloride
-
50% inhibition at 15 mM
Cd2+
-
85% inhibition at 1 mM
Cu2+
-
strong
glycine
-
weak, 30% inhibition at 15 mM
hydroxylamine
Isonicotinic acid hydrazide
L-alanine
-
competitive
L-serine
-
weak, 20% inhibition at 15 mM
Maleic acid
phenylhydrazine
-
pyridoxal phosphate restores activity
Zn2+
-
weak, 25% inhibition at 1 mM
additional information
-