2.6.1.39: 2-aminoadipate transaminase
This is an abbreviated version!
For detailed information about 2-aminoadipate transaminase, go to the full flat file.
Word Map on EC 2.6.1.39
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2.6.1.39
-
5'-phosphate
-
thermus
-
saccharopine
-
aminotransferases
-
thermophilus
-
transamination
-
dicarboxylic
-
semialdehyde
-
kynurenic
-
l-kynurenine
-
2-oxoadipate
-
l-lysine
-
pharmacology
-
medicine
- 2.6.1.39
- 5'-phosphate
-
thermus
- saccharopine
- aminotransferases
- thermophilus
-
transamination
-
dicarboxylic
- semialdehyde
-
kynurenic
- l-kynurenine
- 2-oxoadipate
- l-lysine
- pharmacology
- medicine
Reaction
Synonyms
2-aminoadipate aminotransferase, 2-aminoadipic aminotransferase, AAA-AT, AadAT, AAT, alpha-aminoadipate aminotransferase, alpha-aminoadipate aminotransferase (gene aro8), aminoadipate aminotransferase, aminoadipate aminotransferase/kynurenine aminotransferase II, Aro8, GKAT, glutamate-alpha-ketoadipate transaminase, glutamic-ketoadipic transaminase, halogenated tyrosine aminotransferase, KAT II/AADAT, kynurenine aminotransferase II, kynurenine aminotransferase II (EC 2.6.1.7), kynurenine/alpha-aminoadipate aminotransferase, More
ECTree
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Reference on EC 2.6.1.39 - 2-aminoadipate transaminase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hartline, R.A.
Kynurenine aminotransferase from kidney supernatant
Methods Enzymol.
113
664-672
1985
Rattus norvegicus
Mawal, M.R.; Mukhopadhyay, A.; Deshmukh, D.R.
Purification and properties of kynurenine aminotransferase from rat kidney
Biochem. J.
279
595-599
1991
Rattus norvegicus
-
Mawal, M.R.; Deshmukh, D.R.
alpha-Aminoadipate and kynurenine aminotransferase activities from rat kidney. Evidence for separate identity
J. Biol. Chem.
266
2573-2575
1991
Rattus norvegicus
Takeuchi, F.; Otsuka, H.; Shibata, Y.
Purification, characterization and identification of rat liver mitochondrial kynurenine aminotransferase with alpha-aminoadipate aminotransferase
Biochim. Biophys. Acta
743
323-330
1983
Rattus norvegicus, Rattus norvegicus Wistar
Buchli, R.; Alberati-Giani, D.; Malherbe, P.; Kohler, C.; Broger, C.; Cesura, A.M.
Cloning and functional expression of a soluble form of kynurenine/alpha-aminoadipate aminotransferase from rat kidney
J. Biol. Chem.
270
29330-29335
1995
Rattus norvegicus (Q64602)
Matsuda, M.; Ogur, M.
Separation and specificity of the yeast glutamate-alpha-ketoadipate transaminase
J. Biol. Chem.
244
3352-3358
1969
Saccharomyces cerevisiae
Tobes, M.C.; Mason, M.
L-kynurenine aminotransferase and L-alpha-aminoadipate aminotransferase. I. Evidence for identity
Biochem. Biophys. Res. Commun.
62
390-397
1975
Rattus norvegicus
Tobes, M.C.; Mason, M.
alpha-Aminoadipate aminotransferase and kynurenine aminotransferase. Purification, characterization, and further evidence for identity
J. Biol. Chem.
252
4591-4599
1977
Rattus norvegicus
Deshmukh, D.R.; Mungre, S.M.
Purification and properties of 2-aminoadipate: 2-oxoglutarate aminotransferase from bovine kidney
Biochem. J.
261
761-768
1989
Bos taurus, Rattus norvegicus, Rattus norvegicus Sprague-Dawley
Mawal, M.R.; Deshmukh, D.R.
Purification and properties of alpha-aminoadipate aminotransferase from rat kidney
Prep. Biochem.
21
63-73
1991
Rattus norvegicus
Okuno, E.; Tsujimoto, M.; Nakamura, M.; Kido, R.
2-Aminoadipate-2-oxoglutarate aminotransferase isoenzymes in human liver: a plausible physiological role in lysine and tryptophan metabolism
Enzyme Protein
47
136-148
1993
Homo sapiens
Goh, D.L.; Patel, A.; Thomas, G.H.; Salomons, G.S.; Schor, D.S.; Jakobs, C.; Geraghty, M.T.
Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT)
Mol. Genet. Metab.
76
172-180
2002
Homo sapiens, Homo sapiens (Q8N5Z0)
Miyazaki, T.; Miyazaki, J.; Yamane, H.; Nishiyama, M.
alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus
Microbiology
150
2327-2334
2004
Thermus thermophilus
Tomita, T.; Miyagawa, T.; Miyazaki, T.; Fushinobu, S.; Kuzuyama, T.; Nishiyama, M.
Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus
Proteins
75
348-359
2008
Thermus thermophilus
Ouchi, T.; Tomita, T.; Miyagawa, T.; Kuzuyama, T.; Nishiyama, M.
Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates in alpha-aminoadipate aminotransferase from Thermus thermophilus
Biochem. Biophys. Res. Commun.
388
21-27
2009
Thermus thermophilus (Q72LL6), Thermus thermophilus
Han, Q.; Cai, T.; Tagle, D.A.; Robinson, H.; Li, J.
Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II
Biosci. Rep.
28
205-215
2008
Homo sapiens (Q8N5Z0), Homo sapiens
Han, Q.; Cai, T.; Tagle, D.A.; Li, J.
Structure, expression, and function of kynurenine aminotransferases in human and rodent brains
Cell. Mol. Life Sci.
67
353-368
2010
Mus musculus, Rattus norvegicus, Homo sapiens (Q8N5Z0)
Karsten, W.E.; Reyes, Z.L.; Bobyk, K.D.; Cook, P.F.; Chooback, L.
Mechanism of the aromatic aminotransferase encoded by the Aro8 gene from Saccharomyces cerevisiae
Arch. Biochem. Biophys.
516
67-74
2011
Saccharomyces cerevisiae
Han, Q.; Cai, T.; Tagle, D.; Li, J.
Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases
BMC Biochem.
11
0019
2010
Mus musculus (Q9WVM8)
Rzad, K.; Gabriel, I.
Characterization of two aminotransferases from Candida albicans
Acta Biochim. Pol.
62
903-912
2015
Candida albicans (A0A1D8PG20), Candida albicans ATCC MYA-2876 (A0A1D8PG20)
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