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2.6.1.37: 2-aminoethylphosphonate-pyruvate transaminase

This is an abbreviated version!
For detailed information about 2-aminoethylphosphonate-pyruvate transaminase, go to the full flat file.

Reaction

(2-aminoethyl)phosphonate
+
pyruvate
=
2-phosphonoacetaldehyde
+
L-alanine

Synonyms

(2-aminoethyl)phosphonate aminotransferase, (2-aminoethyl)phosphonate transaminase, (2-aminoethyl)phosphonic acid aminotransferase, 2-aminoethylphosphonate aminotransferase, 2-aminoethylphosphonate-pyruvate aminotransferase, 2-aminoethylphosphonate:pyruvate aminotransferase, aminotransferase, (2-aminoethyl)phosphonate, PA1310, phnW

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.37 2-aminoethylphosphonate-pyruvate transaminase

Substrates Products

Substrates Products on EC 2.6.1.37 - 2-aminoethylphosphonate-pyruvate transaminase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2-aminoethyl)phosphonate + pyruvate
2-phosphonoacetaldehyde + L-alanine
show the reaction diagram
2-aminoethylarsonic acid + pyruvate
alanine + 2-arsonoacetaldehyde
show the reaction diagram
-
-
-
?
2-phosphonoacetaldehyde + D-alanine
(2-aminoethyl)phosphonate + pyruvate
show the reaction diagram
-
L-alanine is preferred but not absolutely required
-
?
alpha-ketoglutarate + L-alanine
L-glutamate + pyruvate
show the reaction diagram
-
0.25% of the kcat observed with 2-phosphonoacetaldehyde
-
?