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2.6.1.2: alanine transaminase

This is an abbreviated version!
For detailed information about alanine transaminase, go to the full flat file.

Word Map on EC 2.6.1.2

Reaction

L-alanine
+
2-oxoglutarate
=
pyruvate
 +
L-glutamate

Synonyms

AAT, AKT, AlaAT, AlaAT1, AlaAT2, alanine aminotransferase, alanine aminotransferase 1, alanine aminotransferase-1, alanine transaminase, alanine-2-oxoglutarate aminotransferase, alanine-alpha-ketoglutarate aminotransferase, alanine-aminotransferase, alanine-pyruvate aminotransferase, alanine: 2-oxoglutarate aminotransferase, ALAT, ALT, ALT1, aminotransferase, alanine, At1g17290, AT3, beta-A:P TAm, beta-alanine aminotransferase, beta-alanine: pyruvate transaminase, Bh D-AlaAT, c-AAT, glutamate pyruvate 2-phosphotransferase, glutamate-pyruvate transaminase, glutamic acid-pyruvic acid transaminase, glutamic-alanine transaminase, glutamic-pyruvic aminotransferase, glutamic-pyruvic transaminase, GmAlaAT, GPT, HvAlaAT, L-alanine aminotransferase, L-alanine transaminase, L-alanine-alpha-ketoglutarate aminotransferase, LOC_Os10g25130, More, OsAlaAT, Pp beta-AlaAT, pyruvate transaminase, pyruvate-alanine aminotransferase, pyruvate-glutamate transaminase, Qsd1, Rp D-AlaAT, ScAlaAT, SkPyd4p, YLSs alanine aminotransferase, ZmAlaAT1, ZmAlaAT2

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.2 alanine transaminase

Substrates Products

Substrates Products on EC 2.6.1.2 - alanine transaminase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-oxoglutarate + 5-aminopentanoate
glutamate + 5-oxopentanoate
show the reaction diagram
-
121% of the activity with beta-alanine
-
?
2-oxoglutarate + 6-aminohexanoate
glutamate + 6-oxohexanoate
show the reaction diagram
-
8% of the activity with beta-alanine
-
?
2-oxoglutarate + DL-3-aminoisobutanoate
glutamate + 3-oxoisobutanoate
show the reaction diagram
-
51% of the activity with beta-alanine
-
?
4-aminobutanoate + 2-oxoglutarate
4-oxobutanoate + glutamate
show the reaction diagram
-
at 131% of the activity with beta-alanine
-
?
4-aminobutanoate + 2-oxoglutarate
4-oxobutanoate + L-glutamate
show the reaction diagram
-
-
-
?
aspartate + 2-oxoglutarate
malate + L-glutamate
show the reaction diagram
14% of activity with glutamate and pyruvate
-
?
aspartate + pyruvate
malate + alanine
show the reaction diagram
10% of activity with alanine and 2-oxoglutarate
-
?
beta-alanine + 2-oxoglutarate
malonic semialdehyde + L-glutamate
show the reaction diagram
-
-
-
?
beta-alanine + glyoxylic acid
malonic semialdehyde + glycine
show the reaction diagram
-
7% of the activity with 2-oxoglutarate
-
?
beta-alanine + pyruvate
malonic semialdehyde + alanine
show the reaction diagram
-
1% of the activity with 2-oxoglutarate
-
?
DL-alanine + 2-oxoglutarate
pyruvate + L-glutamate
show the reaction diagram
glycine + 2-oxoglutarate
glyoxylate + glutamate
show the reaction diagram
-
24% of activity with DL-alanine
-
?
glyoxylate + alanine
glycine + pyruvate
show the reaction diagram
glyoxylate + glutamate
glycine + 2-oxoglutarate
show the reaction diagram
glyoxylate + glutamine
glycine + 2-oxosuccinamate
show the reaction diagram
-
42% of activity with glutamate
-
?
glyoxylate + methionine
glycine + 4-methylsulfanyl-2-oxobutanoate
show the reaction diagram
-
37% of activity with glutamate
-
?
L-alanine + 2-oxobutyrate
pyruvate + 2-aminobutanoate
show the reaction diagram
-
10.2% of the activity with 2-oxoglutarate
-
?
L-alanine + 2-oxoglutarate
pyruvate + L-glutamate
show the reaction diagram
L-alanine + glyoxylate
pyruvate + glycine
show the reaction diagram
L-glutamate and L-alanine are by far the best amino-group donors
-
-
?
L-alanine + glyoxylate
pyruvate + L-glycine
show the reaction diagram
-
-
-
-
ir
L-aspartate + 2-oxoglutarate
2-oxobutan-1,4-dioate + L-glutamate
show the reaction diagram
L-erythrulose + ?
2-amino-1,3,4-butanetriol + ?
show the reaction diagram
-
-
-
-
?
L-glutamate + 2-oxobutyrate
2-oxoglutarate + 2-aminobutanoate
show the reaction diagram
-
32.4% of the activity with pyruvate
-
?
L-glutamate + glyoxylate
2-oxoglutarate + glycine
show the reaction diagram
L-glutamate and L-alanine are by far the best amino-group donors
-
-
?
L-leucine + 2-oxoglutarate
2-oxo-4-methylpentanoate + L-glutamate
show the reaction diagram
L-methionine + 2-oxoglutarate
4-methylsulfanyl-2-oxobutanoate + L-glutamate
show the reaction diagram
-
75% of activity with DL-alanine
-
?
L-methylbenzylamine + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
L-tyrosine + 2-oxoglutarate
(4-hydroxyphenyl)pyruvate + L-glutamate
show the reaction diagram
-
12.5% specific activity compared to L-alanine
-
-
?
L-tyrosine + 2-oxoglutarate
2-deamino-2-oxotyrosine + L-glutamate
show the reaction diagram
-
12-14% of the activity with L-alanine
-
-
?
pyruvate + L-glutamate
L-alanine + 2-oxoglutarate
show the reaction diagram
serine + 2-oxoglutarate
3-hydroxy-2-oxopropanoate + glutamate
show the reaction diagram
-
22% of activity with DL-alanine
-
?
tyrosine + 2-oxoglutarate
3-(4-hydroxyphenyl)-2-oxopropanoate + glutamate
show the reaction diagram
-
36.5% of activity with DL-alanine
-
?
additional information
?
-