2.6.1.2: alanine transaminase

This is an abbreviated version!
For detailed information about alanine transaminase, go to the full flat file.

Reaction

Synonyms

AAT, AKT, AlaAT, AlaAT1, AlaAT2, alanine aminotransferase, alanine aminotransferase 1, alanine aminotransferase-1, alanine transaminase, alanine-2-oxoglutarate aminotransferase, alanine-alpha-ketoglutarate aminotransferase, alanine-aminotransferase, alanine-pyruvate aminotransferase, alanine: 2-oxoglutarate aminotransferase, ALAT, ALT, ALT1, aminotransferase, alanine, At1g17290, AT3, beta-A:P TAm, beta-alanine aminotransferase, beta-alanine: pyruvate transaminase, Bh D-AlaAT, c-AAT, glutamate pyruvate 2-phosphotransferase, glutamate-pyruvate transaminase, glutamic acid-pyruvic acid transaminase, glutamic-alanine transaminase, glutamic-pyruvic aminotransferase, glutamic-pyruvic transaminase, GmAlaAT, GPT, HvAlaAT, L-alanine aminotransferase, L-alanine transaminase, L-alanine-alpha-ketoglutarate aminotransferase, LOC_Os10g25130, More, OsAlaAT, Pp beta-AlaAT, pyruvate transaminase, pyruvate-alanine aminotransferase, pyruvate-glutamate transaminase, Qsd1, Rp D-AlaAT, ScAlaAT, SkPyd4p, YLSs alanine aminotransferase, ZmAlaAT1, ZmAlaAT2

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.1 Transaminases

                2.6.1.2 alanine transaminase

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Results	in table
2	Activating Compound
12130	AA Sequence
9	Application
1	CAS Registry Number
31	Cloned(Commentary)
26	Cofactor
2	Crystallization (Commentary)
31046	Disease/ Diagnostics
14	Expression
5	General Information
5	General Stability
7	IC50 Value
83	Inhibitors
8	kcat/KM [mM/s]
6	Ki Value [mM]
168	KM Value [mM]
27	Localization
58	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
113	Organism
17	Pathway
5	PDB ID
36	pH Optimum
10	pH Range
5	pH Stability
6	pI Value
3	Protein Variants
35	Purification (Commentary)
5	Reaction
1	Reaction Type
109	Reference
97	Source Tissue
35	Specific Activity [micromol/min/mg]
17	Storage Stability
128	Substrates and Products (Substrate)
30	Subunits
116	Synonyms
1	Systematic Name
19	Temperature Optimum [°C]
2	Temperature Range [°C]
7	Temperature Stability [°C]
44	Turnover Number [1/s]

General Stability

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General Stability on EC 2.6.1.2 - alanine transaminase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

during the purification procedure the enzyme needs protective substances, i.e. glycerol, 2-mercaptoethanol and alanine

Solanum lycopersicum

-

636720

enzyme does not tolerate freezing at any stage after sonication of the isolated mitochondria

Sus scrofa

-

636721

K+ or L-alanine stabilizes

Sus scrofa

-

636721

pyridoxal 5'-phosphate, L-alanine or 2-oxoglutarate protects against heat inactivation

Chlamydomonas reinhardtii

-

636723

uneffected by repeated freezing and thawing

Solanum lycopersicum

-

636720