2.6.1.16: glutamine-fructose-6-phosphate transaminase (isomerizing)

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Word Map on EC 2.6.1.16

2.6.1.16

hexosamine

udp-glcnac

albicans

n-acetylglucosamine

glcn6p

o-glcnac

riboswitches

myasthenic

udp-n-acetylglucosamine

o-linked

o-glcnacylation

chitin

self-cleavage

azaserine

self-cleaving

limb-girdle

glutaminase

o-glcnacase

pyridostigmine

fatigable

glucosamine-induced

d-glucosamine

hammerhead

dpagt1

6-diazo-5-oxo-l-norleucine

analysis

synthesis

medicine

Reaction

Synonyms

2-amino-2-deoxy-D-glucose-6-phosphate ketol-isomerase, BsglmS, EC 5.3.1.19, G-6-P synthase, Gfa1, Gfa1p, GFAT, GFAT1, GFAT2, GFPT1, GlcN-6-P synthase, GlmS, glmS ribozyme, glucosamine 6-phosphate synthase, glucosamine 6-phosphate synthetase, glucosamine phosphate isomerase (glutamine-forming), glucosamine synthase, glucosamine-6-P synthase, glucosamine-6-phosphate isomerase (glutamine-forming), glucosamine-6-phosphate synthase, glucosamine-6-phosphate synthetase, glucosamine-6P synthase, glucosamine:fructose-6-phosphate aminotransferase, glutamine-fructose 6-phosphate amidotransferase, glutamine-fructose 6-phosphate aminotransferase, glutamine-fructose-6-phosphate aminotransferase, glutamine-fructose-6-phosphate transaminase 1, glutamine: fructose-6-phosphate amidotransferase, glutamine: fructose-6-phosphate amidotransferase 1, glutamine: fructose-6-phosphate aminotransferase, glutamine:fructose-6-phosphate amidotransferase, glutamine:fructose-6-phosphate aminotransferase, hexosephosphate aminotransferase, isomerase, glucosamine phosphate (glutamine-forming), L-glutamine D-fructose 6-phosphate amidotransferase, L-glutamine fructose 6-phosphate transamidase, L-glutamine: D-fructose-6-phosphate amidotransferase, L-glutamine: L-fructose-6-phosphate amidotransferase, L-glutamine:D-fructose-6-phosphate amidotransferase, L-glutamine:D-fructose-6-phosphate amidotransferase (hexose isomerizing), L-glutamine:D-fructose-6-phosphate amidotransferase (hexose-isomerizing), L-glutamine:L-fructose-6-phosphate amidotransferase

ECTree

2 Transferases

2.6 Transferring nitrogenous groups

2.6.1 Transaminases

2.6.1.16 glutamine-fructose-6-phosphate transaminase (isomerizing)

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Results	in table
9	Activating Compound
53676	AA Sequence
8	Application
1	CAS Registry Number
16	Cloned(Commentary)
5	Cofactor
14	Crystallization (Commentary)
311	Disease/ Diagnostics
31	General Information
13	General Stability
23	IC50 Value
296	Inhibitors
43	Ki Value [mM]
96	KM Value [mM]
35	Molecular Weight [Da]
35	Natural Substrates/ Products (Substrates)
132	Organism
9	Pathway
77	PDB ID
18	pH Optimum
3	pH Range
1	pH Stability
1	pI Value
2	Posttranslational Modification
40	Protein Variants
13	Purification (Commentary)
3	Reaction
1	Reaction Type
117	Reference
47	Source Tissue
33	Specific Activity [micromol/min/mg]
14	Storage Stability
112	Substrates and Products (Substrate)
19	Subunits
146	Synonyms
1	Systematic Name
18	Temperature Optimum [°C]
4	Temperature Stability [°C]
53	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 2.6.1.16 - glutamine-fructose-6-phosphate transaminase (isomerizing)

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chondroitin sulfate B

Congo red

CR, affects the growth, morphology, and activity of glucosamine-6-phosphate synthase in human pathogenic fungus Sporothrix schenckii. Under conditions of yeast development, 0.015 mM CR abolishes conidia germination, but when yeast cells are first obtained in the absence of the dye and then post-incubated in its presence, yeasts rapidly differentiate into mycelial cells. On the other hand, under conditions of mycelium development, 0.150 mM CR do not affect conidia germination, but filamentous cells undergo structural changes characterized by a distorted cell wall contour, the loss of polarity and the formation of red-pigmented, hyphal globose structures. Under these conditions, CR also induces a significant and transient increase in the activity of GlcN-6-P synthase, an essential enzyme in cell wall biogenesis

758706

desferrioxamine

2 entries

dithiothreitol

Saccharomyces cerevisiae

1 mM, activates 1.8fold

639921

Picolinic acid

2 entries

additional information

2 entries