2.6.1.1: aspartate transaminase

This is an abbreviated version!
For detailed information about aspartate transaminase, go to the full flat file.

Word Map on EC 2.6.1.1

2.6.1.1

alt

bilirubin

cholesterol

creatinine

necrosis

albumin

triglyceride

dismutase

hepatotoxicity

malondialdehyde

catalase

hepatoprotective

hepatocytes

wistar

sod

fibrosis

hemoglobin

platelet

glutamic-pyruvic

myocardial

lipoprotein

postoperative

bile

hematological

transpeptidase

tetrachloride

ccl4

infarct

cirrhosis

gg

gamma-glutamyl

uric

admission

transaminases

phosphokinase

albino

jaundice

ccl4-induced

nafld

c-reactive

prothrombin

glutamyl

globulin

gamma-glutamyltransferase

corpuscular

tetrachloride-induced

silymarin

hematocrit

synthesis

kinase-mb

medicine

biotechnology

elastography

Reaction

L-aspartate

+

2-oxoglutarate

=

oxaloacetate

+

L-glutamate

Synonyms

2-oxoglutarate-glutamate aminotransferase, AAT, AAT-2, AAT-3, AAT3, aatA, AATase, aatB3, all2340, alr1039, alr2765, alr4853, aminotransferase, aspartate, aoa/coa, AsAT, Asp AT, aspartate alpha-ketoglutarate transaminase, aspartate aminotransferase, aspartate aminotransferase 1, aspartate aminotransferase A, aspartate AT, aspartate transaminase, aspartate, 2-oxoglutarate aminotransferase, aspartate-2-oxoglutarate transaminase, aspartate/(R)-cysteate:2-oxoglutarate aminotransferase, aspartate/tyrosine/phenylalanine pyridoxal-5'-phosphate-dependent aminotransferase, aspartate:2-oxoglutarate amino-transferase, aspartate:2-oxoglutarate aminotransferase, aspartic acid aminotransferase, aspartic aminotransferase, aspartyl aminotransferase, AspAT, AspATSs, aspB, aspC, AspT, AST, AST-Bb, AtPAT, bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase, C-S lyase, CAA1, cAST, Cgl0240, class Ibeta AAT, EcAspAT, GL50803_91056, glutamate oxaloacetate transaminase, glutamate oxaloacetate transaminase 1, glutamate-oxalacetate aminotransferase, glutamate-oxalate transaminase, glutamate-oxaloacetate transaminase 1, glutamic oxalic transaminase, glutamic oxaloacetic transaminase, glutamic-aspartic aminotransferase, glutamic-aspartic transaminase, glutamic-oxalacetic transaminase, glutamic-oxaloacetic transaminase, GOT, GOT (enzyme), GOT1, GOT1L1, GOT2, KAT IV, L-aspartate aminotransferase, L-aspartate transaminase, L-aspartate-2-ketoglutarate aminotransferase, L-aspartate-2-oxoglutarate aminotransferase, L-aspartate-2-oxoglutarate-transaminase, L-aspartate-alpha-ketoglutarate transaminase, L-aspartate:2-oxoglutarate aminotransferase, L-aspartateartate aminotransferase, L-aspartic aminotransferase, L-AspAT, mitAAT, More, oxaloacetate transferase, oxaloacetate-aspartate aminotransferase, Pat, PfAspAT, plastid aspartate aminotransferase, prephenate aminotransferase, protein TT0402, PT-AAT, Rv3722c, Sar2028, SsAspAT, Tb11.02.2740, transaminase A

ECTree

2.6 Transferring nitrogenous groups

2.6.1 Transaminases

2.6.1.1 aspartate transaminase

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Results	in table
8	Activating Compound
15300	AA Sequence
11	Application
1	CAS Registry Number
44	Cloned(Commentary)
102	Cofactor
39	Crystallization (Commentary)
4727	Disease/ Diagnostics
7	Expression
18	General Information
13	General Stability
59	IC50 Value
159	Inhibitors
40	kcat/KM [mM/s]
52	Ki Value [mM]
260	KM Value [mM]
171	Localization
10	Metals/Ions
107	Molecular Weight [Da]
139	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
881	Organism
59	Pathway
333	PDB ID
75	pH Optimum
16	pH Range
6	pH Stability
28	pI Value
1	Posttranslational Modification
63	Protein Variants
87	Purification (Commentary)
24	Reaction
1	Reaction Type
233	Reference
12	Renatured (Commentary)
144	Source Tissue
107	Specific Activity [micromol/min/mg]
13	Storage Stability
401	Substrates and Products (Substrate)
90	Subunits
320	Synonyms
1	Systematic Name
50	Temperature Optimum [°C]
8	Temperature Range [°C]
51	Temperature Stability [°C]
72	Turnover Number [1/s]

Synonyms

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Synonyms on EC 2.6.1.1 - aspartate transaminase

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2-oxoglutarate-glutamate aminotransferase

-

-

-

-

AAT

show

AAT-2

Triticum aestivum

-

AAT-3

Triticum aestivum

-

AAT3

show

aatA

Sinorhizobium meliloti

-

AATase

show

aatB3

Bacillus subtilis

-

all2340

show

alr1039

show

alr2765

show

alr4853

show

aminotransferase, aspartate

-

-

-

-

aoa/coa

show

AsAT

show

Asp AT

show

aspartate alpha-ketoglutarate transaminase

-

-

-

-

aspartate aminotransferase

show

aspartate aminotransferase 1

-

aspartate aminotransferase A

Sinorhizobium meliloti

-

aspartate AT

show

aspartate transaminase

-

-

aspartate, 2-oxoglutarate aminotransferase

Escherichia coli

-

aspartate-2-oxoglutarate transaminase

-

-

-

-

aspartate/(R)-cysteate:2-oxoglutarate aminotransferase

show

aspartate/tyrosine/phenylalanine pyridoxal-5'-phosphate-dependent aminotransferase

Staphylococcus aureus

-

-

aspartate:2-oxoglutarate amino-transferase

Escherichia coli

-

aspartate:2-oxoglutarate aminotransferase

-

-

-

-

aspartic acid aminotransferase

-

-

-

-

aspartic aminotransferase

-

-

-

-

aspartyl aminotransferase

-

-

-

-

AspAT

show

AspATSs

show

aspB

show

aspC

show

AspT

-

-

-

-

AST

show

AST-Bb

Bubalus bubalis

-

-

AtPAT

Arabidopsis thaliana

-

bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase

Arabidopsis thaliana

UniProt

C-S lyase

show

CAA1

Schizosaccharomyces pombe

-

-

cAST

-

-

Cgl0240

show

class Ibeta AAT

Arabidopsis thaliana

-

EcAspAT

Escherichia coli

wild-type enzyme shows weak desulfination activity and decarboxylation activity

GL50803_91056

show

glutamate oxaloacetate transaminase

-

-

-

-

glutamate oxaloacetate transaminase 1

-

glutamate-oxalacetate aminotransferase

-

-

-

-

glutamate-oxalate transaminase

-

-

-

-

glutamate-oxaloacetate transaminase 1

-

glutamic oxalic transaminase

-

-

-

-

glutamic oxaloacetic transaminase

-

-

glutamic-aspartic aminotransferase

-

-

-

-

glutamic-aspartic transaminase

-

-

-

-

glutamic-oxalacetic transaminase

-

-

-

-

glutamic-oxaloacetic transaminase

-

-

-

-

GOT

show

GOT (enzyme)

-

-

-

-

GOT1

-

737616, 758821, 758917

GOT1L1

-

GOT2

-

KAT IV

Rattus norvegicus

-

-

L-aspartate aminotransferase

show

L-aspartate transaminase

-

-

-

-

L-aspartate-2-ketoglutarate aminotransferase

-

-

-

-

L-aspartate-2-oxoglutarate aminotransferase

-

-

-

-

L-aspartate-2-oxoglutarate-transaminase

-

-

-

-

L-aspartate-alpha-ketoglutarate transaminase

-

-

-

-

L-aspartate:2-oxoglutarate aminotransferase

Rattus norvegicus

-

-

L-aspartateartate aminotransferase

Escherichia coli

-

L-aspartic aminotransferase

-

-

-

-

L-AspAT

Escherichia coli

-

mitAAT

show

oxaloacetate transferase

-

-

-

-

oxaloacetate-aspartate aminotransferase

-

-

-

-

Pat

Arabidopsis thaliana

-

PfAspAT

Plasmodium falciparum

-

-

plastid aspartate aminotransferase

Arabidopsis thaliana

-

-

prephenate aminotransferase

Arabidopsis thaliana

-

protein TT0402

show

PT-AAT

Sorghum bicolor subsp. drummondii

-

the bifunctional enzyme is implicated not only in the aspartate aminotransferase activity but also characterized by a prephenate aminotransferase activity

Rv3722c

show

Sar2028

Staphylococcus aureus

-

-

SsAspAT

Saccharolobus solfataricus

-

Tb11.02.2740

show

transaminase A

-

-

-

-

additional information

show

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Release 2023.1 (January 2023)