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2.5.1.B35: tetratrans,hexacis-undecaprenyl-diphosphate synthase [geranylfarnesyl-diphosphate specific]

This is an abbreviated version!
For detailed information about tetratrans,hexacis-undecaprenyl-diphosphate synthase [geranylfarnesyl-diphosphate specific], go to the full flat file.

Reaction

geranylfarnesyl diphosphate
+ 6 isopentenyl diphosphate = 6 diphosphate +
tetratrans,hexacis-undecaprenyl diphosphate

Synonyms

ape_1385, undecaprenyl diphosphate synthase, UPP synthase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.B35 tetratrans,hexacis-undecaprenyl-diphosphate synthase [geranylfarnesyl-diphosphate specific]

Metals Ions

Metals Ions on EC 2.5.1.B35 - tetratrans,hexacis-undecaprenyl-diphosphate synthase [geranylfarnesyl-diphosphate specific]

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Ca2+
a divalent metal ion is necessary for the activity. Ca2+, Mn2+ and Cu2+ all confer significantly lower activity than Mg2+ does
Cu2+
a divalent metal ion is necessary for the activity. Ca2+, Mn2+ and Cu2+ all confer significantly lower activity than Mg2+ does
Mg2+
a divalent metal ion is necessary for the activity. The addition of 5 mM Mg2+ gives the highest activity within the conditions tested. A 10fold higher concentration of Mg2+ continues to show activity that is comparable to 5 mM Mg2+
Mn2+
a divalent metal ion is necessary for the activity. Ca2+, Mn2+ and Cu2+ all confer significantly lower activity than Mg2+ does