2.5.1.B21: S-adenosyl-L-methionine hydroxide adenosyltransferase

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Reaction

Synonyms

duf-62, duf62, SAM hydroxide adenosyltransferase

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.B21 S-adenosyl-L-methionine hydroxide adenosyltransferase

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Results	in table
1	AA Sequence
4	Cloned(Commentary)
1	Crystallization (Commentary)
1	Inhibitors
3	kcat/KM [mM/s]
1	Ki Value [mM]
4	KM Value [mM]
1	Natural Substrates/ Products (Substrates)
5	Organism
2	Pathway
3	pH Optimum
1	pH Range
4	Protein Variants
3	Purification (Commentary)
1	Reaction
5	Reference
8	Substrates and Products (Substrate)
7	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Stability [°C]
4	Turnover Number [1/s]

Engineering

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Engineering on EC 2.5.1.B21 - S-adenosyl-L-methionine hydroxide adenosyltransferase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

D72A

Salinispora arenicola

-

complete loss of activity

708113

H130A

Salinispora arenicola

-

25% of wild-type activity

708113

H130Y

Salinispora arenicola

-

5% of wild-type activity

708113

R79A

Salinispora arenicola

-

almost inactive protein

708113