2.5.1.93: 4-hydroxybenzoate geranyltransferase
This is an abbreviated version!
For detailed information about 4-hydroxybenzoate geranyltransferase, go to the full flat file.
Word Map on EC 2.5.1.93
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2.5.1.93
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shikonins
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naphthoquinone
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lithospermum
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euchroma
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arnebia
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erythrorhizon
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geranylation
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prenyltransferase
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hairy
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royle
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ubiquinone
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boraginaceae
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acetylshikonin
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mevalonate
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phenylpropanoid
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flask
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ammonia
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prenyl
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contigs
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pyrophosphate
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isobutyrylshikonin
- 2.5.1.93
- shikonins
- naphthoquinone
-
lithospermum
- euchroma
- arnebia
- erythrorhizon
-
geranylation
- prenyltransferase
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hairy
-
royle
- ubiquinone
- boraginaceae
- acetylshikonin
- mevalonate
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phenylpropanoid
-
flask
- ammonia
-
prenyl
-
contigs
- pyrophosphate
- isobutyrylshikonin
Reaction
Synonyms
4HB geranyltransferase, 4HB:geranyltransferase, AePGT, AePGT4, AePGT6, diphosphate:4-hydroxybenzoate geranyltransferase, geranyl diphosphate:4-hydroxybenzoate 3-geranyltransferase, geranyl diphosphate:4-hydroxybenzoate geranyltransferase, lepgt, LePGT-1, LePGT-2, LePGT1, p-hydroxybenzoate geranyltransferase, p-hydroxybenzoate-m-geranyltransferase, p-hydroxybenzoate: geranyltransferase, p-hydroxybenzoate:geranyltransferase, PGT, PGT-1, PHB geranyltransferase, PHBA geranyltransferase
ECTree
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General Information
General Information on EC 2.5.1.93 - 4-hydroxybenzoate geranyltransferase
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evolution
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the phylogenetic tree shows that 4-hydroxybenzoate geranyltransferase (PGT) and 4-hydroxybenzoate polyprenyltransferase (PPT) belong to two different clades
metabolism
physiological function
additional information
LePGT1 is a model membrane-bound aromatic substrate prenyltransferase
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the enzyme catalyzes a key step in the geranyl diphosphate pathway for shikonins biosynthesis, and its couples the mevalonate and the diphosphate pathways, overview
metabolism
the reaction catalyzed by lePGT-1 plays as a competing pathway on two substrates of the Q8 synthesis pathway, namely at IPP and 4-hydroxybenzoate
metabolism
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the enzyme plays an important role in the biosynthesis pathways of shikonin derivatives
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regulatory enzyme in the biosynthesis of shikonin
physiological function
the enzyme is involved in the biosynthesis of a red naphthoquinone pigment, shikonin
physiological function
the enzyme is part of a metabolic strategy to further controll the respiratory levels in CoQ8 biosynthesis-deficient Escherichia coli strains, this metabolic strategy can lead to fine-tuning of aerobic lactate accumulation. The lactate and acetate concentrations increase with increasing enzyme levels, as does the cell density, while glucose concentration decreases, overview