2.5.1.91: all-trans-decaprenyl-diphosphate synthase

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For detailed information about all-trans-decaprenyl-diphosphate synthase, go to the full flat file.

Reaction

Synonyms

AgDPPS, D-less polyprenyl diphosphate synthase, Ddps, ddsa, DdsA protein, decaprenyl diphosphate synthase, decaprenyl diphosphate synthase 1, decaprenyl diphosphate synthase 2, decaprenyl diphosphate synthase gene, decaprenyl-PP synthase, DecPP synthase, decraprenyl diphosphate synthase, DLP1, Dps, DPS1, Rsdds

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.91 all-trans-decaprenyl-diphosphate synthase

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Results	in table
11	Activating Compound
75	AA Sequence
6	Application
21	Cloned(Commentary)
1	Expression
8	General Information
1	General Stability
13	kcat/KM [mM/s]
54	KM Value [mM]
2	Localization
21	Metals/Ions
16	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
31	Organism
3	Pathway
4	pH Optimum
3	pI Value
25	Protein Variants
7	Purification (Commentary)
1	Reaction
30	Reference
1	Source Tissue
34	Substrates and Products (Substrate)
20	Subunits
37	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
12	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 2.5.1.91 - all-trans-decaprenyl-diphosphate synthase

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SYSTEMATIC NAME

IUBMB Comments

(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 7 isopentenyl units)

This enzyme catalyses the condensation reactions resulting in the formation of all-trans-decaprenyl diphosphate, the isoprenoid side chain of ubiquinone-10 and menaquinone-10. The enzyme adds seven isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry.