2.5.1.9: riboflavin synthase

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For detailed information about riboflavin synthase, go to the full flat file.

Word Map on EC 2.5.1.9

2.5.1.9

6,7-dimethyl-8-ribityllumazine

cyclohydrolase

5-amino-6-ribitylamino-2,41h,3h-pyrimidinedione

dismutation

guilliermondii

3,4-dihydroxy-2-butanone

icosahedral

bartonellae

photobacterium

flavinogenic

flavinogenesis

ashbyii

eremothecium

ribitylated

leiognathi

henselae

famata

drug development

pharmacology

medicine

Reaction

2 6,7-dimethyl-8-(1-D-ribityl)lumazine =

4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine

Synonyms

heavy riboflavin synthase, light riboflavin synthase, lumazine synthase/riboflavin synthase complex, RibD, RibE1, riboflavin synthase, riboflavin synthetase, riboflavine synthase, riboflavine synthetase, synthase, riboflavin

ECTree

2 Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.5.1.9 riboflavin synthase

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Results	in table
14	Activating Compound
18084	AA Sequence
6	Application
1	CAS Registry Number
18	Cloned(Commentary)
1	Cofactor
10	Crystallization (Commentary)
3	Expression
5	General Information
5	General Stability
11	IC50 Value
130	Inhibitors
63	Ki Value [mM]
16	KM Value [mM]
5	Metals/Ions
28	Molecular Weight [Da]
75	Natural Substrates/ Products (Substrates)
268	Organism
1	Oxidation Stability
8	Pathway
93	PDB ID
20	pH Optimum
2	pH Range
4	pH Stability
39	Protein Variants
21	Purification (Commentary)
30	Reaction
1	Reaction Type
88	Reference
14	Source Tissue
38	Specific Activity [micromol/min/mg]
8	Storage Stability
128	Substrates and Products (Substrate)
36	Subunits
17	Synonyms
1	Systematic Name
23	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]
7	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 2.5.1.9 - riboflavin synthase

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100000

2 entries

17500

Methanocaldococcus jannaschii

Q58584

5 * 17500, recombinant enzyme

659720

21171

Arabidopsis thaliana

3 * 21171, recombinant enzyme expressed from synthetic gene, electrospray mass spectrometry

658236

22000

Streptomyces davaonensis

Q2VCE7

x * 22000, SDS-PAGE

684754

22043

Bacillus subtilis

3 * 22043, light enzyme, calculation from amino acid sequence

23000

23500

30670

x * 30670, calculated from amino acid sequence

722434

345000

Geobacillus stearothermophilus

gel filtration

66000

67500

recombinant enzyme expressed from synthetic gene, sedimentation equilibrium centrifugation and gel filtration

69000

69800

70000

70000 - 80000

Saccharomyces cerevisiae

analytical ultracentrifugation

637561

75000

2 entries

88300

Methanocaldococcus jannaschii

Q58584

sedimentation equilibrium centrifugation, recombinant enzyme

659720