2.5.1.84: all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]
This is an abbreviated version!
For detailed information about all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific], go to the full flat file.
Word Map on EC 2.5.1.84
Reaction
Synonyms
all-trans-nonaprenyl-diphosphate synthase [geranyl-diphosphate specific], EC 2.5.1.11, nonaprenyl diphosphate synthase, nonaprenylpyrophosphate synthetase, OsSPS1, OsSPS2, solanesyl diphosphate synthase, solanesyl-diphosphate synthase, SolPP synthase, SPP synthase, SPP-synthase, SPS, Sps2, ubiquinone:trans-prenyltransferase
ECTree
2.5.1.84 all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]Advanced search results
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results (Substrates Products
Substrates Products on EC 2.5.1.84 - all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
44% of the rate with geranyl diphosphate
products range from C 15 to C45
-
?
all-trans-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
all-trans-farnesyl methylenediphosphonate + isopentenyl diphosphate
?
-
-
-
-
?
dimethylallyl diphosphate + 8 isopentenyl diphosphate
8 diphosphate + nonaprenyl diphosphate
18.1% of the activity with geranyl diphosphate, OsSPS2
-
-
?
dimethylallyl diphosphate + isopentenyl diphosphate
diphosphate + ?
18% of the rate with geranyl diphosphate
-
-
?
farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + nonaprenyl diphosphate
geranyl diphosphate is the preferred substrate, OsSPS2
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + nonaprenyl diphosphate
34.6% of the activity with geranyl diphosphate, OsSPS2
-
-
?
all-trans-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
-
?
all-trans-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
-
-
all-trans-nonaprenyl diphosphate is the major product
-
?
all-trans-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
-
-
the concentration of the complex between farnesyl diphosphate and Mg2+, the priming substrate for this synthase, does not affect the product distribution, provided that the concentration of isopentenyl diphosphate/Mg2+ is maintained at a certain level. The level of isopentenyl diphosphate/Mg2+ is decisive in affecting the chain length distribution of the products of the prenyltransferase reaction
-
?
all-trans-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
-
-
with MgCl2 nonaprenyl diphosphate is the longest product, with MnCl2 or CoCl2, the longest products are C50 and C55, respectively, partially purified enzyme
-
?
all-trans-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
-
activity with farnesyl diphosphate is lower than with geranyl diphosphate
-
-
?
all-trans-farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
-
about 10% of the activity with geranyl diphosphate
-
-
?
farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
-
?
farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
-
-
variable product specificity depending on Mg2+ concentration. all-trans-Nonaprenyl diphosphate is the longest product
-
?
farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + all-trans-nonaprenyl diphosphate
farnesyl diphosphate is the preferred acceptor substrate
-
-
?
farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + nonaprenyl diphosphate
OsSP2 is involved in the supply of all-trans-nonaprenyl diphosphate for plastoquinone-9 biosynthesis
-
-
?
farnesyl diphosphate + 6 isopentenyl diphosphate
6 diphosphate + nonaprenyl diphosphate
44% of the activity with geranyl diphosphate, OsSPS2
-
-
?
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
-
-
the chain length of the synthesized polyprenyl diphosphate is dependent on the concentration of Mg2+ in the medium. At 0.1 mM Mg2+, C25, C30 and C35 compounds are produced with C25 predominating. At 0.5 mM Mg2+, C25, C30, C35 and C40 compounds are produced with C35 and C40 predominating. At 20 mM Mg2+, C40 and C45 are produced without accumulation od shorter compounds
-
?
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
-
-
variable product specificity depending on Mg2+ concentration. all-trans-Nonaprenyl diphosphate is the longest product
-
?
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
-
the enzyme is involved in the synthesis of the side chain of menaquinone-9
-
-
?
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
-
geranyl diphosphate is the preferred substrate
-
-
?
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
?
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
best substrate
-
-
?
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
geranyl diphosphate is the preferred acceptor substrate
-
-
?
geranyl diphosphate + 7 isopentenyl diphosphate
7 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
-
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
activity with geranylgeranyl diphosphate is lower than with geranyl diphosphate
-
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
35% of the rate with farnesyl diphosphate
products range from C 15 to C45
-
?
geranylgeranyl diphosphate + 5 isopentenyl diphosphate
5 diphosphate + all-trans-nonaprenyl diphosphate
-
about 25% of the activity with geranyl diphosphate
-
-
?
additional information
?
-
-
no activity with geranyl phosphate or dimethylallyl phosphate
-
-
?
additional information
?
-
-
no activity with geranylneryl diphosphate or dimethylallyl diphosphate
-
-
?
additional information
?
-
-
no activity with geranylneryl diphosphate or dimethylallyl diphosphate
-
-
?
