2.5.1.72: quinolinate synthase
This is an abbreviated version!
For detailed information about quinolinate synthase, go to the full flat file.
Word Map on EC 2.5.1.72
-
2.5.1.72
-
nada
-
nicotinamide
-
dihydroxyacetone
-
iminoaspartate
-
iron-sulfur
-
pyrococcus
-
dhap
-
horikoshii
-
qa
-
cluster-containing
-
oxygen-sensitive
-
desulfurase
-
drug development
-
synthesis
- 2.5.1.72
-
nada
- nicotinamide
- dihydroxyacetone
- iminoaspartate
-
iron-sulfur
-
pyrococcus
- dhap
- horikoshii
- qa
-
cluster-containing
-
oxygen-sensitive
-
desulfurase
- drug development
- synthesis
Reaction
Synonyms
Fe4S4 quinolinate synthase, NadA, Old5, PfQS, quinolinate synthetase, SufE3, TM_1644
ECTree
Advanced search results
Metals Ions
Metals Ions on EC 2.5.1.72 - quinolinate synthase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
4Fe-4S cluster
the enzyme requires a [4Fe4S] cluster for full activity
Fe2+
Iron
[4Fe-4S] cluster
-
enzyme contains a [4Fe-4S]-cluster, coordinated by residues C110, C230, C320. 3.8 mol iron per mol of enzyme
Iron
-
protein contains a [4Fe-4S] cluster absolutely required for activity. 3 iron ions per polypeptide
Iron
-
protein contains a [4Fe-4S]2+ cluster plus a small amount of a [3Fe-4S]+ cluster species. Protein contains 5 mol of iron and 2.8 mol of sulfur per mol
Iron
-
sequence contains a Cys-W-X-Cys-Y-Z-Cys sequence characteristic for (Fe-S)4-containing proteins. Enzyme is inhibited by Fe(II)-chelating agents
Iron
-
protein contains a [4Fe-4S] cluster absolutely required for activity
Iron
-
protein contains a [4Fe-4S] cluster absolutely required for activity
an [4Fe-4S] cluster-containing enzyme. The Fe/S cluster of NadA (both Fe4S4 and Fe2S2) might play a significant structural role in NadA that could affect the triose phosphate isomerase activity
[4Fe-4S] cluster
an [4Fe-4S] cluster-containing enzyme. The Fe/S cluster of NadA (both Fe4S4 and Fe2S2) might play a significant structural role in NadA that could affect the triose phosphate isomerase activity
[4Fe-4S] cluster
the presence of the [4Fe-4S] cluster generates an internal tunnel and a cavity