2.5.1.68: (2Z,6E)-farnesyl diphosphate synthase
This is an abbreviated version!
For detailed information about (2Z,6E)-farnesyl diphosphate synthase, go to the full flat file.
Word Map on EC 2.5.1.68
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2.5.1.68
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tuberculosis
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synthases
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decaprenyl
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allylic
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lipoarabinomannan
-
neryl
-
chain-length
-
isoprene
-
mycolyl-arabinogalactan-peptidoglycan
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cis-prenyltransferase
- 2.5.1.68
- tuberculosis
- synthases
-
decaprenyl
-
allylic
- lipoarabinomannan
-
neryl
-
chain-length
- isoprene
-
mycolyl-arabinogalactan-peptidoglycan
- cis-prenyltransferase
Reaction
Synonyms
cis-farnesyl diphosphate synthase, cis-FPS, Mvan 4662, omega,E,Z-FPP, Rv1086, short (C15) chain Z-isoprenyl diphosphate synthase, Z,E-FPP synthase, Z-farnesyl diphosphate synthase, Z-FPP synthase, ZPT1
ECTree
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Substrates Products
Substrates Products on EC 2.5.1.68 - (2Z,6E)-farnesyl diphosphate synthase
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REACTION DIAGRAM
(E)-geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
(E)-neryl diphosphate + isopentenyl diphosphate
(2Z,6Z)-farnesyl diphosphate + diphosphate
8-hydroxygeranyl diphosphate + isopentenyl diphosphate
(2Z)-12-hydroxyfarnesyl diphosphate + (2Z, 6Z)-16-hydroxygeranylgeranyl diphosphate + diphosphate
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16.7% yield of (2Z)-12-hydroxyfarnesyl diphosphate, 6.6% yield of (2Z, 6Z)-16-hydroxygeranylgeranyl diphosphate
-
?
(2Z,6E)-farnesyl diphosphate + diphosphate
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stereospecific reaction
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-
?
(E)-geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
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stereospecific reaction
-
-
?
(2Z,6Z)-farnesyl diphosphate + diphosphate
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stereospecific reaction
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-
?
(E)-neryl diphosphate + isopentenyl diphosphate
(2Z,6Z)-farnesyl diphosphate + diphosphate
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stereospecific reaction
-
-
?
? + diphosphate
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no substrate for wild-type enzyme. Mutant L84A/L85A synthesizes prenyl diphosphates containing 50 carbon atoms
-
?
(E,E)-farnesyl diphosphate + isopentenyl diphosphate
? + diphosphate
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no substrate for wild-type enzyme. Mutant L84A/L85A synthesizes prenyl diphosphates containing 50 carbon atoms
-
?
(2Z,6E)-farnesyl diphosphate + diphosphate
-
-
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
product of wild-type.Mutant L84A/L85A synthesizes prenyl diphosphates containing 20 carbon atoms
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
stereospecific reaction
i.e. omega,E,Z-farnesyl diphosphate
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
step in polyprenylphosphate biosynthesis, overview
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-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
stereospecific reaction
i.e. omega,E,Z-farnesyl diphosphate
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
step in polyprenylphosphate biosynthesis, overview
-
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
product of wild-type.Mutant L84A/L85A synthesizes prenyl diphosphates containing 20 carbon atoms
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
-
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
-
-
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
-
-
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
stereospecific reaction
i.e. omega,E,Z-farnesyl diphosphate
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
step in polyprenylphosphate biosynthesis, overview
-
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
-
-
-
?
geranyl diphosphate + isopentenyl diphosphate
(2Z,6E)-farnesyl diphosphate + diphosphate
-
-
-
-
?
diphosphate + (2Z,6E)-farnesyl diphosphate
-
only geranyl diphosphate is the acceptable substrate among the three allylic substrates, dimethylallyl diphosphate, geranyl diphosphate, and farnesyl diphosphate
-
-
?
geranyl diphosphate + isopentenyl diphosphate
diphosphate + (2Z,6E)-farnesyl diphosphate
-
only geranyl diphosphate is the acceptable substrate among the three allylic substrates, dimethylallyl diphosphate, geranyl diphosphate, and farnesyl diphosphate
-
-
?
geranyl diphosphate + isopentenyl diphosphate
diphosphate + (2Z,6E)-farnesyl diphosphate
-
-
-
?
geranyl diphosphate + isopentenyl diphosphate
diphosphate + (2Z,6E)-farnesyl diphosphate
-
-
-
-
?
geranyl diphosphate + isopentenyl diphosphate
diphosphate + (2Z,6E)-farnesyl diphosphate
-
only geranyl diphosphate is the acceptable substrate among the three allylic substrates, dimethylallyl diphosphate, geranyl diphosphate, and farnesyl diphosphate
-
-
?
geranyl diphosphate + isopentenyl diphosphate
diphosphate + (2Z,6E)-farnesyl diphosphate
-
-
-
?
geranyl diphosphate + isopentenyl diphosphate
diphosphate + (2Z,6E)-farnesyl diphosphate
-
only geranyl diphosphate is the acceptable substrate among the three allylic substrates, dimethylallyl diphosphate, geranyl diphosphate, and farnesyl diphosphate
-
-
?
?
-
the enzyme cannot use dimethylallyl diphosphate as a substrate
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-
?
additional information
?
-
-
the enzyme cannot use dimethylallyl diphosphate as a substrate
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-
?
additional information
?
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the enzyme does not catalyze reactions between 8-tetrahydropyran-2-yloxygeranyl diphosphate and isopentenyl diphosphate
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-
?