2.5.1.66: N2-(2-carboxyethyl)arginine synthase

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For detailed information about N2-(2-carboxyethyl)arginine synthase, go to the full flat file.

Word Map on EC 2.5.1.66

2.5.1.66

clavulanic

clavuligerus

amidinohydrolase

clavams

proclavaminate

cephamycin

beta-lactamase

thiamin

synthesis

protoplast

pset152

transcriptase

thdp-dependent

paralogue

pah1

in-frame

polycistronic

beta-amino

clavaminate

beta-lactam

Reaction

Synonyms

carboxyethylarginine synthase, CEA synthetase, CEAS, CeaS1, ceaS2, N(2)-(2-carboxyethyl)arginine synthase, N2-(2-carboxyethyl)arginine synthetase

ECTree

2 Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.5.1.66 N2-(2-carboxyethyl)arginine synthase

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Results	in table
1	Activating Compound
7	AA Sequence
3	Application
1	CAS Registry Number
5	Cloned(Commentary)
5	Cofactor
2	Crystallization (Commentary)
2	Expression
4	General Information
2	Metals/Ions
5	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
12	Organism
4	Pathway
12	PDB ID
2	Protein Variants
2	Purification (Commentary)
3	Reaction
3	Reaction Type
12	Reference
15	Substrates and Products (Substrate)
4	Subunits
14	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 2.5.1.66 - N2-(2-carboxyethyl)arginine synthase

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glyceraldehyde-3-phosphate:L-arginine N2-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming)

The enzyme requires thiamine diphosphate and catalyses the first step in the clavulanic-acid-biosynthesis pathway. The 2-hydroxy-3-oxo group transferred from glyceraldehyde 3-phosphate is isomerized during transfer to form the 2-carboxyethyl group.