2.5.1.58: protein farnesyltransferase

This is an abbreviated version!
For detailed information about protein farnesyltransferase, go to the full flat file.

Word Map on EC 2.5.1.58

2.5.1.58

farnesylation

prenylation

geranylgeranylation

isoprenoids

beta-subunits

isoprenylation

15-carbon

lamins

manumycin

geranylgeranyltransferase-i

farnesyl-protein

h-ras

medicine

peptidomimetic

prelamin

ggtase-i

p21ras

tetrapeptide

farnesol

tetrahydroquinoline

ras-dependent

pharmacology

progerin

3hmevalonate

ras-induced

lovastatin

tipifarnib

drug development

ras-mediated

ras-transformed

lonafarnib

hutchinson-gilford

dimethylallyl

geranylgeraniol

isoprene

analysis

Reaction

Synonyms

AfFTase, CAAX farnesyltransferase, EhFT, Era1, farnesyl protein transferase, farnesyltransferase, farnesyltransferase ternary complex part II, farnesyltransferase, farnesyl pyrophosphate-protein, farnesyltransferase, protein, FntA, FntB, FPT, fptase, FTase, hFTase, HIT5, Pf-PFT, PfPFT, PFT, PFTase, prenyl transferase, prenylprotein transferase, prenyltransferase, protein cysteine farnesyltransferase, protein farnesyl transferase, protein farnesyltransferase, protein prenyltransferase, protein-farnesyltransferase, R-PFT, Ram1, RAS farnesyltransferase, Ras protein farnesyltransferase, rFPTase, rFTase, rPFTase, TbFTase, yPFTase

Results	in table
2	Activating Compound
3673	AA Sequence
44	Application
1	CAS Registry Number
37	Cloned(Commentary)
17	Crystallization (Commentary)
412	Disease/ Diagnostics
25	General Information
2	General Stability
420	IC50 Value
974	Inhibitors
240	kcat/KM [mM/s]
26	Ki Value [mM]
114	KM Value [mM]
4	Localization
78	Metals/Ions
36	Molecular Weight [Da]
61	Natural Substrates/ Products (Substrates)
5	Organic Solvent Stability
151	Organism
2	Pathway
114	PDB ID
20	pH Optimum
2	pH Range
1	pH Stability
2	pI Value
59	Protein Variants
30	Purification (Commentary)
18	Reaction
145	Reference
39	Source Tissue
6	Specific Activity [micromol/min/mg]
486	Substrates and Products (Substrate)
30	Subunits
145	Synonyms
1	Systematic Name
18	Temperature Optimum [°C]
114	Turnover Number [1/s]

2.5.1.58: protein farnesyltransferase

Reaction

Synonyms

ECTree

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Molecular Weight

Molecular Weight on EC 2.5.1.58 - protein farnesyltransferase