2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase

This is an abbreviated version!
For detailed information about 3-deoxy-7-phosphoheptulonate synthase, go to the full flat file.

Word Map on EC 2.5.1.54

2.5.1.54

shikimate

chorismate

mutase

4.1.2.15

prephenate

l-phenylalanine

feedback-resistant

feedback-insensitive

l-tyrosine

phenylalanine-sensitive

kdo8ps

8-phosphate

tyrosine-sensitive

tryptophan-sensitive

feedback-inhibited

3-deoxy-d-manno-octulosonate

3-dehydroshikimate

arogfbr

l-tyr

3-deoxy-d-manno-octulosonate-8-phosphate

arogenate

synthesis

agriculture

biotechnology

Reaction

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate

Synonyms

2-dehydro-3-deoxy-D-arabino-heptonate-7-phosphate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating), 2-dehydro-3-deoxy-phosphoheptanoate aldolase, 2-dehydro-3-deoxy-phosphoheptonate aldolase, 2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase, 3-deoxy-7-phosphoheptulonate synthase, 3-deoxy-D-arabino heptulosonate 7-phosphate synthase, 3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase, 3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase, 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthase, 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase, 3-deoxy-D-arabinoheptulosonate-7-phosphate synthetase, 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating), 7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating), aldolase, phospho-2-keto-3-deoxyheptanoate, Aro1A, Aro4, Aro4p, AroA, AroA(Q), aroF, AroFFR, AroG, D-erythrose-4-phosphate-lyase, D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating), DAH7-P synthase, DAH7-P synthase (phe), DAH7P, DAH7P synthase, DAH7PS, DAHP synthase, DAHP synthase-phe, DAHP synthase-trp, DAHP synthase-tyr, DAHP(Phe), DAHPS, DAHPS(Tyr), Dax1, deoxy-D-arabino-heptulosonate-7-phosphate synthetase, DHS, DHS1, DS-Co, DS-Mn, EC 4.1.2.15, KDPH synthase, KDPH synthetase, More, mtDAH7Ps, MtDS, NCgl0950 DAHP synthase, NCgl2098 DAHP synthase, Nme-DAH7PS, OsDAHPS, PF1690, phospho-2-dehydro-3-deoxyheptonate aldolase, phospho-2-keto-3-deoxyheptanoate aldolase, Phospho-2-keto-3-deoxyheptonate aldolase, phospho-2-keto-3-deoxyheptonic aldolase, phospho-2-oxo-3-deoxyheptonate aldolase, phzC, TmaDAH7PS

ECTree

2 Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.5.1.54 3-deoxy-7-phosphoheptulonate synthase

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Results	in table
18	Activating Compound
55180	AA Sequence
9	Application
1	CAS Registry Number
34	Cloned(Commentary)
22	Crystallization (Commentary)
2	Expression
24	General Information
17	General Stability
9	IC50 Value
247	Inhibitors
26	kcat/KM [mM/s]
31	Ki Value [mM]
146	KM Value [mM]
12	Localization
95	Metals/Ions
74	Molecular Weight [Da]
41	Natural Substrates/ Products (Substrates)
475	Organism
6	Pathway
224	PDB ID
62	pH Optimum
15	pH Range
2	pH Stability
1	pI Value
69	Protein Variants
56	Purification (Commentary)
31	Reaction
3	Reaction Type
146	Reference
4	Renatured (Commentary)
24	Source Tissue
56	Specific Activity [micromol/min/mg]
7	Storage Stability
194	Substrates and Products (Substrate)
53	Subunits
126	Synonyms
1	Systematic Name
41	Temperature Optimum [°C]
4	Temperature Range [°C]
21	Temperature Stability [°C]
60	Turnover Number [1/s]

Synonyms

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Synonyms on EC 2.5.1.54 - 3-deoxy-7-phosphoheptulonate synthase

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2-dehydro-3-deoxy-D-arabino-heptonate-7-phosphate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating)

2-dehydro-3-deoxy-phosphoheptanoate aldolase

2-dehydro-3-deoxy-phosphoheptonate aldolase

2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase

3-deoxy-7-phosphoheptulonate synthase

2 entries

3-deoxy-D-arabino heptulosonate 7-phosphate synthase

Escherichia coli

672596

3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase

3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase

11 entries

3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase

3-deoxy-D-arabino-heptulosonate-7-phosphate synthase

4 entries

3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthase

Escherichia coli

680370

3-deoxy-D-arabinoheptulosonate 7-phosphate synthase

Escherichia coli

P0AB91

738530

3-deoxy-D-arabinoheptulosonate-7-phosphate synthetase

2 entries

7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating)

7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating)

aldolase, phospho-2-keto-3-deoxyheptanoate

Aro1A

Aro4

Aro4p

Saccharomyces cerevisiae

AroA

AroA(Q)

aroF

AroFFR

AroG

D-erythrose-4-phosphate-lyase

D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating)

DAH7-P synthase

DAH7-P synthase (phe)

DAH7P

DAH7P synthase

DAH7PS

DAHP synthase

DAHP synthase-phe

DAHP synthase-trp

DAHP synthase-tyr

DAHP(Phe)

DAHPS

DAHPS(Tyr)

Dax1

deoxy-D-arabino-heptulosonate-7-phosphate synthetase

DHS

DHS1

DS-Co

plastidic enzyme form

639773

DS-Mn

Petroselinum crispum

cytosolic enzyme form

639773

EC 4.1.2.15

formerly

KDPH synthase

KDPH synthetase

mtDAH7Ps

Mycobacterium tuberculosis

O53512

738155

MtDS

2 entries

NCgl0950 DAHP synthase

Corynebacterium glutamicum

isozyme

684585

NCgl2098 DAHP synthase

Corynebacterium glutamicum

isozyme

684585

Nme-DAH7PS

Neisseria meningitidis

OsDAHPS

PF1690

locus name

phospho-2-dehydro-3-deoxyheptonate aldolase

2 entries

phospho-2-keto-3-deoxyheptanoate aldolase

Phospho-2-keto-3-deoxyheptonate aldolase

phospho-2-keto-3-deoxyheptonic aldolase

phospho-2-oxo-3-deoxyheptonate aldolase

phzC

TmaDAH7PS

additional information

Xanthomonas campestris

2 distinct homology classes: AroAI and AroAII, both being found in bacteria and higher plant chloroplasts, AroAII can be devided into 4 subgroups, phylogenetic evolution

639795