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2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase

This is an abbreviated version!
For detailed information about 3-deoxy-7-phosphoheptulonate synthase, go to the full flat file.

Word Map on EC 2.5.1.54

Reaction

phosphoenolpyruvate
+
D-erythrose 4-phosphate
+
H2O
=
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate
+
phosphate

Synonyms

2-dehydro-3-deoxy-D-arabino-heptonate-7-phosphate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating), 2-dehydro-3-deoxy-phosphoheptanoate aldolase, 2-dehydro-3-deoxy-phosphoheptonate aldolase, 2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase, 3-deoxy-7-phosphoheptulonate synthase, 3-deoxy-D-arabino heptulosonate 7-phosphate synthase, 3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase, 3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase, 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthase, 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase, 3-deoxy-D-arabinoheptulosonate-7-phosphate synthetase, 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating), 7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating), aldolase, phospho-2-keto-3-deoxyheptanoate, Aro1A, Aro4, Aro4p, AroA, AroA(Q), aroF, AroFFR, AroG, D-erythrose-4-phosphate-lyase, D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating), DAH7-P synthase, DAH7-P synthase (phe), DAH7P, DAH7P synthase, DAH7PS, DAHP synthase, DAHP synthase-phe, DAHP synthase-trp, DAHP synthase-tyr, DAHP(Phe), DAHPS, DAHPS(Tyr), Dax1, deoxy-D-arabino-heptulosonate-7-phosphate synthetase, DHS, DHS1, DS-Co, DS-Mn, EC 4.1.2.15, KDPH synthase, KDPH synthetase, More, mtDAH7Ps, MtDS, NCgl0950 DAHP synthase, NCgl2098 DAHP synthase, Nme-DAH7PS, OsDAHPS, PF1690, phospho-2-dehydro-3-deoxyheptonate aldolase, phospho-2-keto-3-deoxyheptanoate aldolase, Phospho-2-keto-3-deoxyheptonate aldolase, phospho-2-keto-3-deoxyheptonic aldolase, phospho-2-oxo-3-deoxyheptonate aldolase, phzC, TmaDAH7PS

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.54 3-deoxy-7-phosphoheptulonate synthase

Molecular Weight

Molecular Weight on EC 2.5.1.54 - 3-deoxy-7-phosphoheptulonate synthase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
103000
-
gel filtration
105000
-
strain JP401, gel filtration
107000
-
Trp-sensitive isozyme, gel filtration
109000
sedimentation equilibrium experiments, tetrameric enzyme
110000
111000
gel filtration, tetrameric enzyme
115000
-
x * 115000, cytosolic isozyme, SDS-PAGE
120000
-
gel filtration
134000
-
gel filtration
135000
-
Trp-sensitive isozyme, gel filtration
136000
-
equilibrium sedimentation
137000
-
DAHP synthase-tyr, gel filtration
140000
-
gel filtration and sedimentation equilibrium analysis
141000
homotetrameric wild-type enzyme, analytical ultracentrifugation
150000
homotetrameric wild-type enzyme, gel filtration
156000
-
gel filtration
175000
-
DAHP synthase-trp, gel filtration
200000
-
tryptophan-sensitive isozyme, sedimentation equilibrium centrifugation
251000
-
DAHP synthase-tyr, gel filtration
253000
-
gel filtration
29159
2 * 30000, SDS-PAGE, 2 * 29159, calculated
29224
-
2 * 29226, ESI-MS, 2 * 29224, calculated
29226
-
2 * 29226, ESI-MS, 2 * 29224, calculated
30000
2 * 30000, SDS-PAGE, 2 * 29159, calculated
33000
-
x * 33000, SDS-PAGE
35000
38000
-
4 * 38000, SDS-PAGE
385000 - 443000
-
gel filtration
39000
40000
400000
-
gel filtration
42000
42130
-
1 * 42130, calculation from nucleotide sequence
50000
-
2 * 50000, native isozyme NCgl2098 DAHP synthase, gel filtration
50511
-
5 * 50511, ESI-MS, 5 * 50640, calculated
50640
-
5 * 50511, ESI-MS, 5 * 50640, calculated
51000
-
x * 51000, SDS-PAGE
51830
52000
-
4 * 52000, tryptophan-sensitive isozyme, SDS-PAGE
53000
54000
55400
gel filtration
5700
-
gel filtration
58450
-
ESI-MS
59000
66000
67000
-
DAHP synthase-phe, gel filtration
69000
71000
-
Tyr-sensitive isozyme, mutant N8K, gel filtration
75000
-
Tyr-sensitive isozyme, wild-type, gel filtration
77000
sedimentation velocity data, apo protein
78000
sedimentation velocity data, in complex with tyrosine
84000
-
native NCgl0950 DAHP synthase, gel filtration
97000
-
gel filtration