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2.5.1.49: O-acetylhomoserine aminocarboxypropyltransferase

This is an abbreviated version!
For detailed information about O-acetylhomoserine aminocarboxypropyltransferase, go to the full flat file.

Word Map on EC 2.5.1.49

Reaction

O-acetyl-L-homoserine
+
methanethiol
=
L-methionine
 +
acetate

Synonyms

AHS, EC 4.2.99.10, gamma-cyano-alpha-aminobutyric acid synthase, Homocysteine synthase, MetC, methionine synthase, MetY, O-acetyl-L-homoserine (thiol)-lyase, O-acetyl-L-homoserine acetate-lyase (adding methanethiol), O-acetyl-L-homoserine sulfhydrolase, o-acetyl-L-homoserine sulfhydrylase, O-acetylhomoserine sulfhydrolase, O-acetylhomoserine sulfhydrylase, OAH, OAH SHase, OAH SHLase, OAH sulfhydrylase, OAH-OAS sulfhydrylase, oah2 gene product, OAHS, OAS-OAH sulfhydrylase, Q187D4

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase

KM Value

KM Value on EC 2.5.1.49 - O-acetylhomoserine aminocarboxypropyltransferase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
40
ethanol
Corynebacterium acetophilum
-
-
0.053 - 2.4
H2S
0.4
hydrogen sulfide
pH 7.5, 25°C
4.17
L-homocysteine
-
at 45°C, pH 7.5
10.4
L-homoserine
-
-
4
L-serine-O-sulfate
-
NaHS or Na2Se as donor
0.4
methanethiol
pH 7.5, 25°C
0.8
methyl-mercaptan
-
-
10
Na2Se
-
L-serine-O-sulfate as acceptor
1.2
NaHSe
-
L-serine-O-sulfate as acceptor
0.6 - 13
O-acetyl-L-homoserine
2.5 - 5.12
O-acetyl-L-serine
11.1
O-succinyl-L-homoserine
-
-
0.52 - 0.7
S2-