2.5.1.48: cystathionine gamma-synthase
This is an abbreviated version!
For detailed information about cystathionine gamma-synthase, go to the full flat file.
Word Map on EC 2.5.1.48
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2.5.1.48
-
homocystinuria
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transsulfuration
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beta-lyase
-
gamma-lyase
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sulfhydrylase
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o-acetylhomoserine
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gamma-replacement
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l-cystathionine
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cystathionase
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o-phosphohomoserine
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paucicostata
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gamma-elimination
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homocystine
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s-methylmethionine
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remethylation
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synthesis
- 2.5.1.48
- homocystinuria
-
transsulfuration
-
beta-lyase
-
gamma-lyase
-
sulfhydrylase
- o-acetylhomoserine
-
gamma-replacement
- l-cystathionine
- cystathionase
- o-phosphohomoserine
- paucicostata
-
gamma-elimination
- homocystine
- s-methylmethionine
-
remethylation
- synthesis
Reaction
Synonyms
AtCGS, CGS, CGS1, CS,26, cystathionine gamma-synthase, cystathionine synthase, cystathionine synthetase, cystathionine-gamma-synthase, EC 4.2.99.9, homoserine O-transsuccinylase, homoserine transsuccinylase, HTS, MetB, O-succinyl-L-homoserine succinate-lyase (adding cysteine), O-succinylhomoserine (Thiol)-lyase, O-succinylhomoserine synthase, O-succinylhomoserine synthetase, synthase, cystathionine gamma-
ECTree
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Systematic Name
Systematic Name on EC 2.5.1.48 - cystathionine gamma-synthase
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O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase
A pyridoxal-phosphate protein. Also reacts with hydrogen sulfide and methanethiol as replacing agents, producing homocysteine and methionine, respectively. In the absence of thiol, can also catalyse beta,gamma-elimination to form 2-oxobutanoate, succinate and ammonia.