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2.5.1.47: cysteine synthase

This is an abbreviated version!
For detailed information about cysteine synthase, go to the full flat file.

Word Map on EC 2.5.1.47

Reaction

O-acetyl-L-serine
+
hydrogen sulfide
=
L-cysteine
 +
acetate

Synonyms

(OAS-TL)-like protein, acetylserine sulfhydrylase, At-OASS, ATCC 23270 protein, BAbS19_I09950, beta-cyano-alanine synthase, beta-cyano-L-alanine synthase, CS-A, CS-B, CS1, CS26, CS3, CSase, CSase A, CSase B, CSaseLP, CSC, Cys synthase complex, cysK, CysK1, CysK2, CYSL, CysL-1, cysl-2, CysM, Cysteine synthase, cysteine synthase 1, cysteine synthase A, cysteine synthase B, cysteine synthase, chloroplastic/chromoplastic, cysteine synthase, mitochondrial, cysteine synthetase, DcsD, EC 4.2.99.8, EhCS, EhCS1, EhCS3, EhOASS, Fn1220, GmOAS-TL1, GmOAS-TL2, GmOAS-TL3, GmOAS-TL4, GmOAS-TL6, GmOAS-TL7, GmOASTL4, GsOAS-TL1, GYY4137, HiOASS, HiOASS-A, lanthionine synthase, LbrCS, MCSA1, Nt-OAS-TL, O -acetylserine (thiol)-lyase, O-acetyl-L-serine (thiol) lyase, O-acetyl-L-serine acetate-lyase (adding hydrogen sulfide), O-acetyl-L-serine sulfhydrylase, O-acetyl-L-serine sulfhydrylase B, O-acetyl-L-serine sulfohydrolase, O-acetyl-L-serine(thiol)lyase, O-acetyl-serine (thiol) lyase, O-acetylserine (thiol) lyase, O-acetylserine (Thiol)-lyase, O-acetylserine (thiol)-lyase A, O-acetylserine (thiol)-lyase B, O-acetylserine (thiol)lyase, O-acetylserine sulfhydrylase, O-acetylserine sulfhydrylase A, O-acetylserine sulfhydrylase B, O-acetylserine sulfhydrylase isoenzyme B, O-acetylserine sulfhydrylase-A, O-acetylserine sulfhydrylase-B, O-acetylserine thiol lyase, O-acetylserine(thiol)lyase, O-acetylserine-(thiol)lyase, O-acetylserine-O-acetylhomoserine sulfhydro-lyase, O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase, OAS Shase, OAS thiol-lyases, OAS-TL, OAS-TL A, OAS-TL B, OAS-TL C, OASA1, OASB, OASS, OASS-A, OASS-B, OASTL, OASTL-A, OASTL-A1, old3-1, OPSS, Os01g0290600, Os03g53650, protein ONSET OF LEAF DEATH 3, RCS3, S-sulfocysteine synthase, SSC synthase, StOASTL A, StOASTL B, sulfhydrylase/cysteine synthase, synthase, cysteine, TvCS1

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.47 cysteine synthase

IC50 Value

IC50 Value on EC 2.5.1.47 - cysteine synthase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0101
3-[[(3,4-dichlorophenyl)carbamoyl]amino]benzoic acid
Mycobacterium tuberculosis
pH not specified in the publication, temperature not specified in the publication
0.0066
3-[[([1,1'-biphenyl]-3-yl)carbamoyl]amino]benzoic acid
Mycobacterium tuberculosis
pH not specified in the publication, temperature not specified in the publication
0.0177
4-(2-methylphenyl)-8-nitro-2-thioxo-2,3,4,4a-tetrahydro-5H-pyrimido[5,4-e][1,3]thiazolo[3,2-a]pyrimidin-5-one
Mycobacterium tuberculosis
pH not specified in the publication, temperature not specified in the publication
0.0227
4-(4-methoxyphenyl)-8-nitro-2-thioxo-2,3,4,4a-tetrahydro-5H-pyrimido[5,4-e][1,3]thiazolo[3,2-a]pyrimidin-5-one
Mycobacterium tuberculosis
pH not specified in the publication, temperature not specified in the publication
0.0269
4-[[([1,1'-biphenyl]-3-yl)carbamoyl]amino]-2-hydroxybenzoic acid
Mycobacterium tuberculosis
pH not specified in the publication, temperature not specified in the publication
0.0299
5-[[(3,4-dichlorophenyl)carbamoyl]amino]-2-hydroxybenzoic acid
Mycobacterium tuberculosis
pH not specified in the publication, temperature not specified in the publication
0.0103
5-[[([1,1'-biphenyl]-3-yl)carbamoyl]amino]-2-hydroxybenzoic acid
Mycobacterium tuberculosis
pH not specified in the publication, temperature not specified in the publication
0.0303
8-nitro-4-(2-nitrophenyl)-2-thioxo-2,3,4,4a-tetrahydro-5H-pyrimido[5,4-e][1,3]thiazolo[3,2-a]pyrimidin-5-one
Mycobacterium tuberculosis
pH not specified in the publication, temperature not specified in the publication
0.0177
8-nitro-4-[2-(trifluoromethyl)phenyl]-4,4a-dihydro-2H-pyrimido[5,4-e][1,3]thiazolo[3,2-a]pyrimidine-2,5(3H)-dione
Mycobacterium tuberculosis
pH not specified in the publication, temperature not specified in the publication
0.00064 - 0.00098
aggreticin
0.021 - 0.022
deacetylkinamycin C
0.053 - 0.057
deoxyfrenolicin
0.00031 - 0.00063
kerriamycin B
0.00056 - 0.0012
kerriamycin C
0.053 - 0.065
nanaomycin A
0.075 - 0.49
naphthacemycin A
0.47 - 0.49
patulin
0.217 - 0.233
pencolide
0.17 - 0.19
tetracycline
additional information
deoxyfrenolicin