2.5.1.38: isonocardicin synthase

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Reaction

Synonyms

aminocarboxypropyltransferase, nocardicin, nocardicin aminocarboxypropyltransferase

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.38 isonocardicin synthase

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1	AA Sequence
1	CAS Registry Number
1	General Stability
1	Natural Substrates/ Products (Substrates)
1	Organism
4	Pathway
1	Purification (Commentary)
1	Reaction
1	Reaction Type
1	Reference
2	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 2.5.1.38 - isonocardicin synthase

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SYSTEMATIC NAME

IUBMB Comments

S-adenosyl-L-methionine:nocardicin-G 3-amino-3-carboxypropyltransferase

The enzyme, characterized from the bacterium Nocardia uniformis, is involved in the biosynthesis of the beta-lactam antibiotic nocardicin A. The enzyme can act on nocardicin E, F, and G, producing isonocardicin A, B, and C, respectively. However, the in vivo substrate is believed to be nocardicin G [3].