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2.5.1.29: geranylgeranyl diphosphate synthase

This is an abbreviated version!
For detailed information about geranylgeranyl diphosphate synthase, go to the full flat file.

Word Map on EC 2.5.1.29

Reaction

(2E,6E)-farnesyl diphosphate
+
isopentenyl diphosphate
=
diphosphate
 +
geranylgeranyl diphosphate

Synonyms

At4g36810, bifunctional farnesyl/geranylgeranyl diphosphate synthase, BTS1, CcGGDPS1, CcGGDPS2, CotB1, CrtE, DR1395, EgcrtE, EuFPS1, EuFPS2, farnesyl diphosphate/geranylgeranyl diphosphate synthase, farnesyl-diphosphate/geranylgeranyldiphosphate, farnesyltransferase, FPPS/GGPPS, geranylgeranyl diphosphate synthase, geranylgeranyl diphosphate synthase 1, geranylgeranyl diphosphate synthase 11, geranylgeranyl pyrophosphate synthase, geranylgeranyl pyrophosphate synthase GACE1337, geranylgeranyl pyrophosphate synthase GGPPS1-1, geranylgeranyl pyrophosphate synthase GGPPS1-2, geranylgeranyl pyrophosphate synthetase, geranylgeranyl-PP synthetase, geranylgeranyl-pyrophosphate synthase, GGDP synthase, GGDPS, GGPP synthase, GGPP-S, GGPPase, GGPPS, GGPPS 1, GGPPS 191, GGPPS 2, GGPPS 3, GGPPS 595, GGPPS 727, GGPPS1, GGPPS11, GGPS, Ggps1, GGs1, GgsA, GgsB, GGSP1, gps, HpGGPPS, HsGGPPS, IbGGPS, IdsA, isoprenyl diphosphate synthase, leaf-specific geranylgeranyl pyrophosphate synthase, More, PaxG, PfFPPS, PfGGPPS, Saci_0092, short-chain type-III GGPP, synthetase, geranylgeranyl pyrophosphate, TgFPPS, Tk-IdsA, trans-prenyl diphosphate synthase, type II geranylgeranyl diphosphate synthase, type-III geranylgeranyl pyrophosphate synthase, type-III GGPPS

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.29 geranylgeranyl diphosphate synthase

Molecular Weight

Molecular Weight on EC 2.5.1.29 - geranylgeranyl diphosphate synthase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
130000
-
tetramer, non-denaturing PAGE
150000
-
Superose 12, gel filtration
158000
-
recombinant His-tagged enzyme, gel filtration
190000
-
Superdex 200, gel filtration
200000
-
about, gel filtration
240000
-
octamer, non-denaturing PAGE
30000
-
2 * 30000, the native enzyme consists of 2 identical subunits with a tendency to dissociate, SDS-PAGE
300000
31500
2 * 31500, deduced from nucleotide sequence
32000
-
2 * 32000, recombinant enzyme, SDS-PAGE
36800
-
x * 36800, SDS-PAGE
36873
x * 36873, calculated from sequence
37000
-
2 * 37000, SDS-PAGE
37500
-
x * 37500, tetramer or pentamer, SDS-PAGE
38000
38326
2 * 38326, calculation from nucleotide sequence
39000
39900
x * 39900, about, isozyme GGPPS1, sequence calculation
40000
41600
x * 41600, about, sequence calculation
44790
recombinant mutant H139A/R140A, gel filtration
47820
recombinant monomeric mutant M111E, gel filtration
55000
x * 55000, SDS-PAGE, recombinant protein including His-tag
60000
61000
66000
-
gel filtration
70000
72000
-
gel filtration
72070
recombinant mutant N101A/Y105A, gel filtration
74000
74740
recombinant mutant Y105A, gel filtration
75000
gel filtration
75950
recombinant mutant N101A, gel filtration
76000
-
gel filtration
76730
recombinant mutant N104A/Y105A, gel filtration
76990
recombinant mutant R140A, gel filtration
78690
recombinant mutant H139A, gel filtration
80350
recombinant mutant N104A, gel filtration
82300
recombinant wild-type enzyme, gel filtration
83880
recombinant mutant N101A/N104A/Y105A, gel filtration
84000
-
recombinant His-tagged enzyme, gel filtration
84980
recombinant mutant N101A/N104A, gel filtration
85000
85920
recombinant dimeric mutant M111E, gel filtration
88080
recombinant mutant M111F, gel filtration
92340
recombinant mutant M111A, gel filtration