2.5.1.23: sym-norspermidine synthase

This is an abbreviated version!
For detailed information about sym-norspermidine synthase, go to the full flat file.

Reaction

Synonyms

HbSpe 1, propylaminc transferase

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.23 sym-norspermidine synthase

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Results	in table
6	AA Sequence
1	Cloned(Commentary)
2	Expression
8	IC50 Value
10	Inhibitors
1	Ki Value [mM]
5	KM Value [mM]
2	Localization
6	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
24	Organism
3	Pathway
2	pH Optimum
1	pH Range
1	pI Value
2	Purification (Commentary)
1	Reaction
1	Reaction Type
7	Reference
1	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
14	Substrates and Products (Substrate)
7	Subunits
3	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Range [°C]
5	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 2.5.1.23 - sym-norspermidine synthase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

S-adenosyl 3-(methylthio)propylamine + propane-1,3-diamine

S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine

2 entries

S-adenosyl 3-(methylthio)propylamine + spermidine

S-methyl-5'-thioadenosine + thermospermine + H+

2 entries

S-adenosylmethioninamine + propane-1,3-diamine

5'-methylthioadenosine + N-(3-aminopropyl)-1,3-diaminopropane

2 entries

S-adenosylmethioninamine + propane-1,3-diamine

5'-S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine

2 entries

S-adenosylmethioninamine + putrescine

5'-S-methyl-5'-thioadenosine + spermidine

2 entries

S-adenosylmethioninamine + spermidine

5'-S-methyl-5'-thioadenosine + spermine

2 entries

S-adenosylmethioninamine + sym-norspermidine

5'-S-methyl-5'-thioadenosine + ?

2 entries

S-adenosyl 3-(methylthio)propylamine + propane-1,3-diamine

S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine

Hyperthermus butylicus

A2BJU2

-

727512

-

-

?

S-adenosyl 3-(methylthio)propylamine + propane-1,3-diamine

S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine

Hyperthermus butylicus DSM 5456

A2BJU2

-

727512

-

-

?

S-adenosyl 3-(methylthio)propylamine + spermidine

S-methyl-5'-thioadenosine + thermospermine + H+

Hyperthermus butylicus

A2BJU2

at 5% of the specific activity compared to propane-1,3-diamine

727512

-

-

?

S-adenosyl 3-(methylthio)propylamine + spermidine

S-methyl-5'-thioadenosine + thermospermine + H+

Hyperthermus butylicus DSM 5456

A2BJU2

at 5% of the specific activity compared to propane-1,3-diamine

727512

-

-

?

S-adenosylmethioninamine + propane-1,3-diamine

5'-methylthioadenosine + N-(3-aminopropyl)-1,3-diaminopropane

Euglena gracilis

-

-

638427

-

-

?

S-adenosylmethioninamine + propane-1,3-diamine

5'-methylthioadenosine + N-(3-aminopropyl)-1,3-diaminopropane

Euglena gracilis

-

i.e. decarboxylated S-adenosylmethionine + 1,3-diaminopropane

638427

i.e. sym-norspermidine

638427

?

S-adenosylmethioninamine + propane-1,3-diamine

5'-S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine

Saccharolobus solfataricus

-

-

719387

-

-

ir

S-adenosylmethioninamine + propane-1,3-diamine

5'-S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine

Saccharolobus solfataricus MT-4 / DSM 5833

-

-

719387

-

-

ir

S-adenosylmethioninamine + putrescine

5'-S-methyl-5'-thioadenosine + spermidine

Saccharolobus solfataricus

-

36.7% of the activity compared to activity with 1,3-diaminopropane, propylamine transfer is operated through a sequential mechanism

719387

-

-

ir

S-adenosylmethioninamine + putrescine

5'-S-methyl-5'-thioadenosine + spermidine

Saccharolobus solfataricus MT-4 / DSM 5833

-

36.7% of the activity compared to activity with 1,3-diaminopropane, propylamine transfer is operated through a sequential mechanism

719387

-

-

ir

S-adenosylmethioninamine + spermidine

5'-S-methyl-5'-thioadenosine + spermine

Saccharolobus solfataricus

-

6.8% of the activity compared to activity with 1,3-diaminopropane, propylamine transfer is operated through a sequential mechanism

719387

-

-

ir

S-adenosylmethioninamine + spermidine

5'-S-methyl-5'-thioadenosine + spermine

Saccharolobus solfataricus MT-4 / DSM 5833

-

6.8% of the activity compared to activity with 1,3-diaminopropane, propylamine transfer is operated through a sequential mechanism

719387

-

-

ir

S-adenosylmethioninamine + sym-norspermidine

5'-S-methyl-5'-thioadenosine + ?

Saccharolobus solfataricus

-

17.5% of the activity compared to activity with 1,3-diaminopropane, propylamine transfer is operated through a sequential mechanism

719387

-

-

ir

S-adenosylmethioninamine + sym-norspermidine

5'-S-methyl-5'-thioadenosine + ?

Saccharolobus solfataricus MT-4 / DSM 5833

-

17.5% of the activity compared to activity with 1,3-diaminopropane, propylamine transfer is operated through a sequential mechanism

719387

-

-

ir