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2.5.1.20: rubber cis-polyprenylcistransferase

This is an abbreviated version!
For detailed information about rubber cis-polyprenylcistransferase, go to the full flat file.

Word Map on EC 2.5.1.20

Reaction

poly-cis-polyprenyl diphosphate
+
isopentenyl diphosphate
=
diphosphate
+
a poly-cis-polyprenyl diphosphate longer by one C5 unit

Synonyms

allyltransferase, rubber, chain-elongating enzyme cis-prenyltransferase, cis prenyl transferase, cis-1,4-polyprenylcistransferase, cis-prenyl transferase, cis-prenyltransferase, cisprenyltransferase, CPT, CPT3, CPT6, HRT1, HRT2, isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase, laticifer-specific rubber-forming enzyme, More, RT-ase complex, rTase, rubber allyltransferase, rubber polymerase, rubber prenyltransferase, rubber transferase, rubber transferase 1, rubber transferase 2, rubber transferase complex, RubCPT1, TkCPT1, TkCPT2, TkCPT3, TkCPTL1

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.20 rubber cis-polyprenylcistransferase

Inhibitors

Inhibitors on EC 2.5.1.20 - rubber cis-polyprenylcistransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(Z)-2-farnesyl-3-methylbutenedioic acid dilithium salt
(Z)-2-octyl-3-methylbutenedioic acid dilithium salt
-
i.e. SG-2–96, 40% inhibition at 0.18 mM
alpha-hydroxyfarnesylphosphonic acid
chaetomellic acid
Co2+
-
0.1-1 mM, complete inhibition
diphosphate
-
-
farnesyl diphosphate
-
-
iodoacetamide
iodoacetic acid
-
-
N-ethylmaleimide
-
-
p-chloromercuribenzoate
-
50 mM, strong inhibition
Sodium diphosphate
-
-
Sodium phosphate
-
-
Thiol alkylating agents
-
-
-
Zn2+
-
0.1-1 mM, complete inhibition
additional information
-
not inhibitory: (Z)-2-octyl-3-methylbutenedioic acid dilithium salt
-