2.5.1.2: thiamine pyridinylase
This is an abbreviated version!
For detailed information about thiamine pyridinylase, go to the full flat file.
Word Map on EC 2.5.1.2
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2.5.1.2
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thiaminolyticus
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medicine
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thiazole
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aniline
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pseudoharengus
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viscera
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bivalve
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alosa
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analysis
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nutrition
- 2.5.1.2
- thiaminolyticus
- medicine
- thiazole
- aniline
- pseudoharengus
- viscera
-
bivalve
-
alosa
- analysis
- nutrition
Reaction
Synonyms
pyrimidine transferase, thiamin hydrolase, thiamin pyridinolase, thiamin pyridinylase, thiaminase, thiaminase I, thiamine pyridinolase, thiamine pyridinylase
ECTree
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pI Value
pI Value on EC 2.5.1.2 - thiamine pyridinylase
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5.7
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the liver of Fisturalia petimba contains thiaminase I of at least three different pIs and the major fraction exhibits pI 5.7. The most evident difference among pI isozymes is the size of the active subfragments into which they are dissociated. pI 5.7 enzyme dissociates into subfragments of 25 kDa, while pI 7-9 enzymes dissociates into approximately 22000 Da. The reaction rate measured by pyridine as the second substrate is three times higher in pI 7-9 enzymes compared with pI 5.7 enzyme. The degree of cadmium inhibition, when aniline is the cosubstrate, shows obvious differences between pI isozymes