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2.5.1.2: thiamine pyridinylase

This is an abbreviated version!
For detailed information about thiamine pyridinylase, go to the full flat file.

Word Map on EC 2.5.1.2

Reaction

thiamine
+
Pyridine
=
1-[(4-amino-2-methylpyrimidin-5-yl)methyl]pyridinium
+
4-methyl-5-(2-hydroxyethyl)thiazole

Synonyms

pyrimidine transferase, thiamin hydrolase, thiamin pyridinolase, thiamin pyridinylase, thiaminase, thiaminase I, thiamine pyridinolase, thiamine pyridinylase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.2 thiamine pyridinylase

Temperature Optimum

Temperature Optimum on EC 2.5.1.2 - thiamine pyridinylase

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TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
25
in 50 mM sodium phosphate at pH 7
45
-
pI 5.7 isoenzyme, pI 7-9 isoenzym, thiamine + 2-mercaptoethanol
45 - 55
-
pI 5.7 isoenzyme, pI 7-9 isoenzym, thiamine + aniline