2.5.1.2: thiamine pyridinylase

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For detailed information about thiamine pyridinylase, go to the full flat file.

Word Map on EC 2.5.1.2

2.5.1.2

thiaminolyticus

medicine

thiazole

aniline

pseudoharengus

viscera

bivalve

alosa

analysis

nutrition

Reaction

1-[(4-amino-2-methylpyrimidin-5-yl)methyl]pyridinium

Synonyms

pyrimidine transferase, thiamin hydrolase, thiamin pyridinolase, thiamin pyridinylase, thiaminase, thiaminase I, thiamine pyridinolase, thiamine pyridinylase

ECTree

2 Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.5.1.2 thiamine pyridinylase

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Results	in table
50	Activating Compound
111	AA Sequence
13	Application
1	CAS Registry Number
2	Cloned(Commentary)
2	Crystallization (Commentary)
21	General Information
62	Inhibitors
8	kcat/KM [mM/s]
2	Ki Value [mM]
62	KM Value [mM]
12	Localization
2	Metals/Ions
9	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
121	Organism
1	Oxidation Stability
2	Pathway
24	PDB ID
19	pH Optimum
5	pH Range
9	pH Stability
1	pI Value
7	Protein Variants
9	Purification (Commentary)
1	Reaction
1	Reaction Type
117	Reference
130	Source Tissue
4	Specific Activity [micromol/min/mg]
105	Substrates and Products (Substrate)
3	Subunits
28	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
17	Temperature Range [°C]
10	Turnover Number [1/s]

Source Tissue

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Source Tissue on EC 2.5.1.2 - thiamine pyridinylase

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eye

Celosia crista

less activity than in leaves

636845

frond

5 entries

gastrointestinal tract

Celosia crista

scarcely found

lush growth

scarcely found

very low activity

additional information

Clupea harengus

thiaminase activity of undigested Baltic herring (Clupea harengus membras) found in Baltic salmon (Salmo salar) stomachs is significantly higher than that of trawl-caught Baltic herring from the same sea area, suggesting that there may be a higher risk of predation for Baltic herring with high thiaminase activity, possibly linked to their health. Thiaminase activity of the gastrointestinal contents of Baltic salmon, feeding almost entirely on Baltic herring in the Gulf of Bothnia, is significantly higher than for Baltic salmon feeding on both Baltic herring and sprat in the Gulf of Bothnia. Therefore, Baltic herring may be the major source of thiaminase for Baltic salmon. A tank experiment demonstrates that thiaminase activity in Baltic herring may vary, even within very short time periods

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