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2.5.1.18: glutathione transferase

This is an abbreviated version!
For detailed information about glutathione transferase, go to the full flat file.

Word Map on EC 2.5.1.18

Reaction

RX
+
glutathione
=
HX
+
R-S-glutathione

Synonyms

2-hydroxychromene-2-carboxylic acid isomerase, 26GST, adGSTD4-4, agGSTe2, allergen Der p 2, allergen Der p 8, alpha class glutathione transferase, Alpha class GST, alpha GST, alpha-class glutathione transferase, asGST5.5, AtGSTF2, AtuGSTH1-1, BaeAB, beta-etherase, bmGSTD, BphK, CgGSTM1, CgGSTM2, cGST, Chi class GST, Chi GST, class mu glutathione S-transferase, delta class glutathione transferase, delta-class glutathione S-transferase, Delta-class glutathione transferase, EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14, EC 4.4.1.7, EGST, epsilon class GST, Epsilon glutathione S-transferase, Epsilon glutathione transferase, Epsilon GST, epsilon-class glutathione S-transferase, epsilon-class glutathione transferase, GHR, glutathione S-alkyl transferase, glutathione S-aralkyltransferase, glutathione S-aryltransferase, glutathione S-transferase, glutathione S-transferase 2, glutathione S-transferase A1-1, glutathione S-transferase A3-3, glutathione S-transferase AdFSTD3-3, glutathione S-transferase I, glutathione S-transferase omega 1, glutathione S-transferase omega 2, glutathione S-transferase P1-1, glutathione S-transferase pi, glutathione S-transferase Pi-1, glutathione S-transferase X, glutathione transferase, glutathione transferase A1-1, glutathione transferase A4-4, glutathione transferase M1-1, glutathione transferase M2-2, glutathione transferase Omega 3S, glutathione transferase omega-1, glutathione transferase P1-1, glutathione transferase Pi, glutathione transferase T1-1, glutathione transferase zeta, glutathione transferase zeta 1, glutathione transferase Zeta 1-1, glutathione transferase zeta1-1, glutathione transferase-like protein, glutathione-S-transferas, glutathione-S-transferase, glutathione-S-transferase pi, glutathione-transferase, GmGSTU4-4, GSH S-transferase, GSH transferase, GSH transferase homologue, GSH-S transferase rho, GSHTase-P, GST, GST A1-1, GST A2-2, GST A3-3, GST A4-4, GST adgstD4-4, GST alpha, GST Delta 2, GST I, GST II, GST III, GST IV, GST M1-1, GST M2-2, GST M4-4, GST M5-5, GST mu, GST O1-1, GST P1-1, GST pi, GST T1-1, GST Tau, GST Tau19, GST Z1-1, GST-1, GST-2, GST-26, GST-3, GST-Acr, GST-OCX-32, GST-T, GST-theta, GST1, GST1b, GST2, GST20, GST3, GST4, GST5, GST5118, GST7, GST83044, Gsta, GSTA1, GSTA1-1, GSTA2-2, GSTA3, GSTA3-3, GSTA4, GSTA4-4, GSTA4L, GSTA5, GSTA5-5, GSTalpha1, GSTD, GSTD1, GSTD10, GSTd14, GSTD2, GSTD4, GSTD4-4, GSTE1, GSTE2, GSTE3, GSTE4, GSTE5, GSTE6, GSTE7, GSTE8, GSTF12-1, GSTF12-2, GSTF3, GSTF5, GSTF9, GSTFuA1, GSTk, GSTK1, GSTL1, GSTL2, GSTL3, Gstm, GSTm09, GSTM1, GSTM1-1, GSTM2, GSTM2-2, GSTM3, GSTM3-3, GSTM4, GSTM4-4, GSTM5, GSTM5-5, GSTmu, GSTO, GSTO1, GSTO1-1, GSTO2, GSTO2-2, GstO2A, GstO2B, GSTO3, GSTO3S, GSTO4, GSTO7, GSTP, GSTP 1-1, GSTP-1, GSTP1, GSTP1-1, Gstr1, GSTrho, GSTS, GSTS1, GSTS1-1, GSTS2, GSTS3, GSTT, GSTT1, GSTT1-1, Gstt1a, GSTT2, GSTT2-2, GSTT2B-2B, GSTT4, GSTT4L, GSTU1, GSTU10, GSTU10-10, GSTU11, GSTU12, GSTU13, GSTU13-1, GSTU14, GSTU16, GSTU17, GSTU18, GSTU19, GSTU2, GSTU2-2, GSTU21, GSTU24, GSTU24-1, GSTU25, GSTU26, GSTU28, GSTU3, GSTU4, GSTU45, GSTU5, GSTU6, GSTU7, GSTU8, GSTU9, GSTZ, Gstz1, GSTZ1-1, GTT1.2, HCCA isomerase, Hematopoietic prostaglandin D synthase, hGSTA-3, hGSTA1-1, hGSTZ1-1, kappa class glutathione transferase, kappa class GSH transferase, Kappa class GST, KKSG9, lambda glutathione transferase, MAAI, MGST1, MGST2, MGST3, Mgst3a, Mgst3b, microsomal glutathione transferase 1, microsomal glutathione transferase-1, More, mtMGST1, mu class glutathione S-transferase, Mu class GST, mu glutathione transferase, Mu GST, mu-class glutathione S-transferase, mu-class glutathione S-transferase1, Mu-class GST, Mu-GST, nu-class glutathione transferase, Omega class GST, omega glutathione S-transferase, omega glutathione transferase, omega-class glutathione S-transferase, omega-class glutathione S-transferase 2, pGSTA1, phi class glutathione transferase, Pi class GST, pm-GSTR1, PmGST, PtGSTU1, PvGSTF1-1, PvGSTU2-2, PvGSTU3-3, rho class glutathione S-transferase, rho-GST, RX: glutathione R-transferase, RX:glutathione R-transferase, S-(hydroxyalkyl)glutathione lyase, Saro_2873/Saro_2872, selenium-containing glutathione transferase zeta1-1, seleno-hGSTZ1-1, SGST26.5, sigma class glutathione transferase, Sigma class GST, sigma glutathione S-transferase, sigma-class glutathione S-transferase, sigma-class GST, SIGST, Sj26GST, sjGST, sll1545, ssGST3, ssGST5, tau class glutathione S-transferase, tau class glutathione transferase, tau class GST, tau class GSTU4-4, TDR1, theta class glutathione S-transferase, theta class glutathione transferase T1-1, theta class GST, theta-class glutathione transferase, thiol-dependent reductase I, Ure2p mutant A122C, Ure2pB1, Xi class glutathione transferase, Ya-GST, YghU, zeta class glutathione S-transferase, Zeta class GST

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.18 glutathione transferase

Molecular Weight

Molecular Weight on EC 2.5.1.18 - glutathione transferase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
recombinant tetrameric enzyme, gel filtration
104000
-
gel filtration
14000
-
SDS-PAGE
19420
-
1 * 23310 + 1 * 20430, enzyme of Nanyang city population, SDS-PAGE, 1 * 53140 + 1 * 20130, enzyme of Wuzhou population, SDS-PAGE, 1 * 50790 + 1 * 19420, enzyme of Hezhou population, SDS-PAGE
20130
-
1 * 23310 + 1 * 20430, enzyme of Nanyang city population, SDS-PAGE, 1 * 53140 + 1 * 20130, enzyme of Wuzhou population, SDS-PAGE, 1 * 50790 + 1 * 19420, enzyme of Hezhou population, SDS-PAGE
20430
-
1 * 23310 + 1 * 20430, enzyme of Nanyang city population, SDS-PAGE, 1 * 53140 + 1 * 20130, enzyme of Wuzhou population, SDS-PAGE, 1 * 50790 + 1 * 19420, enzyme of Hezhou population, SDS-PAGE
22000
22500
22800
-
2 * 22800 or 2 * 24600, SDS-PAGE
23000
23100
isozyme GSTS2, calculated from amino acid sequence
23204
x * 23204, sequence calculation
23310
-
1 * 23310 + 1 * 20430, enzyme of Nanyang city population, SDS-PAGE, 1 * 53140 + 1 * 20130, enzyme of Wuzhou population, SDS-PAGE, 1 * 50790 + 1 * 19420, enzyme of Hezhou population, SDS-PAGE
23338
x * 23338, GSTO, sequence calculation
23400
-
2 * 23400, SDS-PAGE
23500
23548
-
x * 25348-25528, alpha class isozyme, mass spectrometry, x * 23548, pi class isozyme, MALDI-TOF mass spectrometry, x * 26027, mu class isozyme, MALDI-TOF mass spectrometry
24000
24100
-
2 * 24100, SDS-PAGE
24225
x * 24225, GSTO, sequence calculation
24300
-
x * 24300, recombinant His6-tagged wild-type GSTZ1-1, SDS-PAGE
24400
-
2 * 24400, SDS-PAGE
24500
24600
25100
25180
x * 25180, GSTU17, sequence calculation
25200
-
2 * 25200, form I-XII, SDS-PAGE
25280
-
-
25452
2 * 25452, recombinant isozyme GSTT1, mass spectrometry and SDS-PAGE
25500
25600
25630
His-tagged wild type enzyme, calculated from amino acid sequence
25705
-
x * 25705, isozyme Der p 8, sequence calcualtion
25800
-
MALDI-TOF mass spectrometry
25900
-
2 * 25900, MALDI-TOF mass spectrometry
26027
-
x * 25348-25528, alpha class isozyme, mass spectrometry, x * 23548, pi class isozyme, MALDI-TOF mass spectrometry, x * 26027, mu class isozyme, MALDI-TOF mass spectrometry
26400
-
2 * 26400, isoenzyme VI, SDS-PAGE
26500
26660
calculated from amino acid sequence
26700
2 * 26700, isozyme SIGST, SDS-PAGE
26800
26900
-
x * 27400, HdGSTO1, sequence calculation, x * 26900, HdGSTO2, sequence calculation
27000
-
2 * 27000, SDS-PAGE
27100
27200
-
1 * 28000 + 1 * 27200, gel filtration
27328
2 * 27328, electrospray ionization MS
27400
-
x * 27400, HdGSTO1, sequence calculation, x * 26900, HdGSTO2, sequence calculation
27500
28000
28700
29000
29806
x * 29806, GSTO, sequence calculation
30000
31800
2 * 31800, SDS-PAGE
32600
-
1 * 32600 + 1 * 36800, enzyme occurs as homodimeric form and as heterodimeric form, SDS-PAGE
34000
-
2 * 34000, enzyme occurs as homodimeric form and as heterodimeric form, SDS-PAGE
36800
-
1 * 32600 + 1 * 36800, enzyme occurs as homodimeric form and as heterodimeric form, SDS-PAGE
43000
-
gel filtration
44000
gel filtration
45000
45000 - 47000
-
sedimentation equilibrium analysis, gel filtration
45000 - 49000
45000 - 50000
-
-
45000 - 60000
-
gel filtration
46000
47000
47500
-
GSH-S transferase rho, gel filtration
47900
enzyme form GSTR1, gel filtration
48000
48000 - 54000
-
gel filtration
49000
49000 - 54000
-
gel filtration
49200
-
gel filtration
49500
-
native PAGE
49850
SEC-MALS analysis
50790
-
1 * 23310 + 1 * 20430, enzyme of Nanyang city population, SDS-PAGE, 1 * 53140 + 1 * 20130, enzyme of Wuzhou population, SDS-PAGE, 1 * 50790 + 1 * 19420, enzyme of Hezhou population, SDS-PAGE
51000
-
recombinant enzyme, gel filtration
52000
-
SDS-PAGE
53000
53140
-
1 * 23310 + 1 * 20430, enzyme of Nanyang city population, SDS-PAGE, 1 * 53140 + 1 * 20130, enzyme of Wuzhou population, SDS-PAGE, 1 * 50790 + 1 * 19420, enzyme of Hezhou population, SDS-PAGE
54000
-
isoform GST1, gel filtration
56000
gel filtration
58000
fusion protein GST-OCX-32, SDS-PAGE
59000
Q2G4B4; Q2G4B5
gel filtration
60000
65000
recombinant His-tagged enzyme, SDS-PAGE
88000
-
gel filtration, isoenzyme 2.1
additional information
-
monomer-dimer equilibrium and average molecular weights with and without bound glutathione at different concentrations of KBr, overview