2.5.1.16: spermidine synthase

This is an abbreviated version!
For detailed information about spermidine synthase, go to the full flat file.

Reaction

Synonyms

aminopropyltransferase, aminopropyltransferase spermidine synthase, AtSPDS1, AtSPDS2, MdSPDS1, PAPT, PgSPD, putrescine aminopropyltransferase, Spd synthase, SPDS, SPDS2, SPDSYN, spe-sdh, spe3, SpeE, spermidine synthase, spermidine synthase 1, spermidine synthetase, Spm synthase, SpSyn, Synpcc7942_0628, synthase, spermidine

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.16 spermidine synthase

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Results	in table
2	Activating Compound
21026	AA Sequence
5	Application
1	CAS Registry Number
40	Cloned(Commentary)
4	Cofactor
14	Crystallization (Commentary)
93	Disease/ Diagnostics
2	Expression
30	General Information
14	General Stability
10	IC50 Value
198	Inhibitors
6	kcat/KM [mM/s]
10	Ki Value [mM]
51	KM Value [mM]
6	Localization
13	Metals/Ions
53	Molecular Weight [Da]
73	Natural Substrates/ Products (Substrates)
650	Organism
7	Pathway
196	PDB ID
27	pH Optimum
5	pH Range
4	pH Stability
2	pI Value
24	Protein Variants
42	Purification (Commentary)
15	Reaction
1	Reaction Type
125	Reference
118	Source Tissue
18	Specific Activity [micromol/min/mg]
18	Storage Stability
206	Substrates and Products (Substrate)
41	Subunits
80	Synonyms
1	Systematic Name
37	Temperature Optimum [°C]
4	Temperature Range [°C]
8	Temperature Stability [°C]
22	Turnover Number [1/s]

General Stability

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General Stability on EC 2.5.1.16 - spermidine synthase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

dialysis against glycine-NaOH buffer, pH 8.8 inactivates

Brassica rapa subsp. pekinensis

-

489871, 639704

DTT and/or EDTA do not stabilize

Brassica rapa subsp. pekinensis

-

489871, 639704

DTT stabilizes

Rattus norvegicus

-

639709

freeze-thawing inactivates

3 entries

heat-inactivated enzyme preparation does not restore the activity

Brassica rapa subsp. pekinensis

-

639704

S-adenosyl-(5')-3-methylthio-1-propylamine protects from inhibitors when preincubated

Glycine max

-

639714

tetramerization stabilizes

Thermotoga maritima

-

639718

very labile in crude extracts

Brassica rapa subsp. pekinensis

-

489871

freeze-thawing inactivates

Escherichia coli

-

639706, 639707, 639709

freeze-thawing inactivates

Rattus norvegicus

-

639709

freeze-thawing inactivates

Glycine max

-

639714