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2.5.1.132: 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase

This is an abbreviated version!
For detailed information about 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase, go to the full flat file.

Word Map on EC 2.5.1.132

Reaction

phosphoenolpyruvate
+
D-mannose 6-phosphate
+
H2O
=
3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate
+
phosphate

Synonyms

2-keto-3-deoxy-D-glycero-D-galacto-9-phosphonononic acid synthase, 2-keto-3-deoxy-D-glycero-D-galacto-nonulosonic acid 9-phosphate synthase, 3-deoxy-D-glycero-D-galacto-nononate 9-phosphate synthase, BT1714, KDN 9-phosphate synthase, KDN-9-P synthase, KDN-9-phosphate synthetase, KDN-9P synthase, N-acetylneuraminic acid phosphate synthase, Neu5Ac 9-phosphate synthase, neu5ac-9-P synthase, NeuNAc-9-P synthase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.132 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase

Cloned

Cloned on EC 2.5.1.132 - 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21(DE3) Gold cells
-
expressed in Escherichia coli BL21-AI cells
-
the gene partially restores sialic acid synthase activity in a neuB-negative mutant of Escherichia coli and results in N-acetylneuraminic acid (Neu5Ac) and 2-dehydro-3-deoxy-D-glycero-D-galacto-nononic acid production in insect cells upon recombinant baculovirus infection