2.5.1.128: N4-bis(aminopropyl)spermidine synthase
This is an abbreviated version!
For detailed information about N4-bis(aminopropyl)spermidine synthase, go to the full flat file.
Reaction
2 S-adenosyl 3-(methylsulfanyl)propylamine + = 2 S-methyl-5'-thioadenosine +
Synonyms
BpsA, TK1691
ECTree
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Systematic Name
Systematic Name on EC 2.5.1.128 - N4-bis(aminopropyl)spermidine synthase
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S-adenosyl 3-(methylthio)propylamine:spermidine 3-aminopropyltransferase (N4-bis(aminopropyl)spermidine synthesizing)
The enzyme, characterized from the thermophilic archaeon Thermococcus kodakarensis, synthesizes the branched-chain polyamine N4-bis(aminopropyl)spermidine, which is required for cell growth at high-temperature. When spermine is used as substrate, the enzyme forms N4-aminopropylspermine.