2.5.1.127: caldopentamine synthase

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For detailed information about caldopentamine synthase, go to the full flat file.

Reaction

Synonyms

HbSpe II, long-chain polyamine synthase

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.127 caldopentamine synthase

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Results	in table
1	AA Sequence
1	Cloned(Commentary)
2	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
2	Organism
3	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
2	Reference
4	Specific Activity [micromol/min/mg]
16	Substrates and Products (Substrate)
4	Subunits
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 2.5.1.127 - caldopentamine synthase

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SYSTEMATIC NAME

IUBMB Comments

S-adenosyl 3-(methylthio)propylamine:norspermine 3-aminopropyltransferase

The enzyme, characterized from the thermophilic archaeon Hyperthermus butylicus, can also synthesize norspermine from norspermidine and thermospermine from spermidine (with lower activity). The long-chain polyamines stabilize double-stranded DNA at high temperatures. In contrast to EC 2.5.1.23, sym-norspermidine synthase and EC 2.5.1.126, norspermine synthase, this enzyme shows no activity with propane-1,3-diamine.