2.5.1.115: homogentisate phytyltransferase
This is an abbreviated version!
For detailed information about homogentisate phytyltransferase, go to the full flat file.
Word Map on EC 2.5.1.115
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2.5.1.115
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tocopherol
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tocotrienols
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alpha-tocopherol
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geranylgeranyl
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gamma-tocopherol
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phytylation
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prenylation
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synechocystis
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tocochromanols
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prenyltransferase
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lipid-soluble
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tocopherol-deficient
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seed-specific
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agriculture
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nutrition
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synthesis
- 2.5.1.115
- tocopherol
-
tocotrienols
- alpha-tocopherol
-
geranylgeranyl
- gamma-tocopherol
-
phytylation
-
prenylation
- synechocystis
-
tocochromanols
- prenyltransferase
-
lipid-soluble
-
tocopherol-deficient
-
seed-specific
- agriculture
- nutrition
- synthesis
Reaction
Synonyms
At2g18950, HPT, HPT1, RTD1, slr1736, SynHPT, VTE2, VTE2-1, VTE2-2, VTE2.1
ECTree
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Substrates Products
Substrates Products on EC 2.5.1.115 - homogentisate phytyltransferase
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REACTION DIAGRAM
geranylgeranyl diphosphate + homogentisate
diphosphate + 2-methyl-6-geranylgeranylbenzene-1,4-diol + CO2
geranylgeranyl diphosphate + homogentisate
diphosphate + 2-methyl-6-geranylgeranylbenzoquinol + CO2
-
-
-
?
geranylgeranyl diphosphate + homogentisate
diphosphate + 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2
about 18% of the activity with phythyldiphosphate
-
-
?
phytyl diphosphate + homogentisate
diphosphate + 2-methyl-6-phytylbenzoquinol + CO2
-
-
-
?
diphosphate + 2-methyl-6-geranylgeranylbenzene-1,4-diol + CO2
-
-
-
?
geranylgeranyl diphosphate + homogentisate
diphosphate + 2-methyl-6-geranylgeranylbenzene-1,4-diol + CO2
-
-
-
?
diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
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-
-
?
phytyl diphosphate + homogentisate
diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
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-
-
-
?
phytyl diphosphate + homogentisate
diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
the enzyme is involved in the biosynthesis of the vitamin E tocopherols
-
-
?
phytyl diphosphate + homogentisate
diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
no activity with geranylgeranyl diphosphate, no activity with solanesyl diphosphate
-
-
?
phytyl diphosphate + homogentisate
diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
-
-
-
?
phytyl diphosphate + homogentisate
diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
-
-
-
-
?
phytyl diphosphate + homogentisate
diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
-
-
-
?
phytyl diphosphate + homogentisate
diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
-
-
-
-
?
phytyl diphosphate + homogentisate
diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
preferred substrate
-
-
?
phytyl diphosphate + homogentisate
diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
the enzyme is involved in the biosynthesis of the vitamin E tocopherols
-
-
?
phytyl diphosphate + homogentisate
diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
phytyl diphosphate and homogentisate are the preferred substrates in vito, no activity with solanesyl diphosphate
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-
?
?
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enzyme is more active with phythyl diphosphate than with geranylgeranyl diphosphate but inactive with solanesyl diphosphate or farnesyl diphosphate
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-
?
additional information
?
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recombinant Arabidopsis thaliana HPT preferentially catalyzes in vitro production of the tocotrienol precursor geranylgeranyl benzoquinol only when presented with high molar ratios of geranylgeranyl diphosphate:phytyl diphosphate
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-
?
additional information
?
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enzyme is more active with phythyl diphosphate than with geranylgeranyl diphosphate but inactive with solanesyl diphosphate or farnesyl diphosphate
-
-
?
additional information
?
-
no substrate: solanesyl diphosphate
-
-
?