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2.5.1.106: tryprostatin B synthase

This is an abbreviated version!
For detailed information about tryprostatin B synthase, go to the full flat file.

Word Map on EC 2.5.1.106

Reaction

dimethylallyl diphosphate
+
brevianamide F
=
diphosphate
 +
tryprostatin B

Synonyms

brevianamide F prenyltransferase, cyclic dipeptide C2-prenyltransferase FtmPT1, FtmPT1, indole prenyltransferase, tryprostatin B synthase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.106 tryprostatin B synthase

Turnover Number

Turnover Number on EC 2.5.1.106 - tryprostatin B synthase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.4
(E)-4-(1H-indol-3-yl)but-3-en-2-one
pH not specified in the publication, temperature not specified in the publication
4.05 - 5.57
brevianamide F
0.25 - 1.39
cyclo-(D-Trp-D-Pro)
0.06 - 0.24
cyclo-(D-Trp-L-Ala)
0.21 - 0.41
cyclo-(D-Trp-L-Pro)
0.71
cyclo-(L-Trp-D-Ala)
pH 7.5, 37°C, prenylation at C2
0.18 - 0.32
cyclo-(L-Trp-D-Pro)
2.55 - 3.14
cyclo-(L-Trp-Gly)
0.13 - 1.47
cyclo-(L-Trp-L-Ala)
21.14
cyclo-(L-Trp-L-His)
pH 7.5, 37°C, prenylation at C2
1.36 - 8.9
cyclo-(L-Trp-L-Pro)
0.09 - 1.73
cyclo-(L-Trp-L-Tyr)