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2.5.1.106: tryprostatin B synthase

This is an abbreviated version!
For detailed information about tryprostatin B synthase, go to the full flat file.

Word Map on EC 2.5.1.106

Reaction

dimethylallyl diphosphate
+
brevianamide F
=
diphosphate
 +
tryprostatin B

Synonyms

brevianamide F prenyltransferase, cyclic dipeptide C2-prenyltransferase FtmPT1, FtmPT1, indole prenyltransferase, tryprostatin B synthase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.106 tryprostatin B synthase

KCat KM Value

KCat KM Value on EC 2.5.1.106 - tryprostatin B synthase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
25.3
brevianamide F
pH 7.5, 37°C, prenylation at C2
0.78 - 4.9
cyclo-(D-Trp-D-Pro)
0.43 - 0.61
cyclo-(D-Trp-L-Ala)
0.53 - 0.89
cyclo-(D-Trp-L-Pro)
1.73
cyclo-(L-Trp-D-Ala)
pH 7.5, 37°C, prenylation at C2
0.52 - 2.2
cyclo-(L-Trp-D-Pro)
3.69 - 4.08
cyclo-(L-Trp-Gly)
0.27 - 2.72
cyclo-(L-Trp-L-Ala)
4.76
cyclo-(L-Trp-L-His)
pH 7.5, 37°C, prenylation at C2
12 - 156
cyclo-(L-Trp-L-Pro)
0.25 - 6.41
cyclo-(L-Trp-L-Tyr)