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2.5.1.101: N,N'-diacetyllegionaminate synthase

This is an abbreviated version!
For detailed information about N,N'-diacetyllegionaminate synthase, go to the full flat file.

Word Map on EC 2.5.1.101

Reaction

2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose
+
phosphoenolpyruvate
+
H2O
=
N,N'-diacetyllegionaminate
+
phosphate

Synonyms

legI, N,N'-diacetyllegionaminic acid synthase, NeuB, NeuB homologue, nonulosonic acid synthase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.101 N,N'-diacetyllegionaminate synthase

Systematic Name

Systematic Name on EC 2.5.1.101 - N,N'-diacetyllegionaminate synthase

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SYSTEMATIC NAME
IUBMB Comments
phosphoenolpyruvate:2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose 1-(2-carboxy-2-oxoethyl)transferase
Requires a divalent metal such as Mn2+. Isolated from the bacteria Legionella pneumophila and Campylobacter jejuni, where it is involved in the biosynthesis of legionaminic acid, a virulence-associated, cell surface sialic acid-like derivative.