2.4.2.9: uracil phosphoribosyltransferase

This is an abbreviated version!
For detailed information about uracil phosphoribosyltransferase, go to the full flat file.

Reaction

Synonyms

AFR052C, AFR052Cp, AGOS_AFR052C, AgUPRT, CD-UPRT, cytosine deaminase-uracil phosphoribosyltransferase, cytosine deaminase/uracil phosphoribosyltransferase, More, MtUPRT, phosphoribosyltransferase, uracil, Rv3309c, TtUPRT, TtUPRT3, UK/UPRT1, UMP pyrophosphorylase, UMP:pyrophosphate phosphoribosyltransferase, UPP, UPRT, UPRTase, uracil phosphoribosyl transferase, uridine 5'-phosphate pyrophosphorylase, uridine kinase-like protein (uracil phosphoribosyltransferase), uridine kinase/uracil phosphoribosyltransferase 1, uridine monophosphate pyrophosphorylase, uridylate pyrophosphorylase, uridylic pyrophosphorylase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.9 uracil phosphoribosyltransferase

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Results	in table
22	Activating Compound
44618	AA Sequence
15	Application
1	CAS Registry Number
34	Cloned(Commentary)
7	Crystallization (Commentary)
312	Disease/ Diagnostics
24	General Information
10	General Stability
1	IC50 Value
49	Inhibitors
5	Ki Value [mM]
46	KM Value [mM]
4	Localization
43	Metals/Ions
33	Molecular Weight [Da]
32	Natural Substrates/ Products (Substrates)
368	Organism
5	Pathway
104	PDB ID
21	pH Optimum
7	pH Range
2	pI Value
20	Protein Variants
21	Purification (Commentary)
10	Reaction
1	Reaction Type
66	Reference
30	Source Tissue
19	Specific Activity [micromol/min/mg]
12	Storage Stability
109	Substrates and Products (Substrate)
36	Subunits
88	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
2	Temperature Range [°C]
14	Temperature Stability [°C]
8	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 2.4.2.9 - uracil phosphoribosyltransferase

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TEMPERATURE STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

40

Tetrahymena pyriformis

-

irreversible inactivation above

638360

45

Bacillus subtilis

-

10 min, 90% remaining activity

638370

50

Toxoplasma gondii

-

begins to unfold irreversibly

638367

55

2 entries

56 - 57

Escherichia coli

-

10 min, 50% loss of activity, recombinant wild-type and mutant, scanning calorimetry

638372

60

2 entries

65

Toxoplasma gondii

-

complete inactivation after 5 min

638367

70

[Bacillus] caldolyticus

P70881

10 min, 70% remaining activity

638370

75

[Bacillus] caldolyticus

P70881

10 min, 5% remaining activity

638370

80

2 entries

90

Saccharolobus shibatae

-

half-life: 4 min

678368

55

Bacillus subtilis

-

10 min, 20% remaining activity

638370

55

Candida albicans

-

4 min, complete loss of activity

638366

60

Bacillus subtilis

-

10 min, inactivation

638370

60

Saccharomyces cerevisiae

-

2 min, complete loss of activity, 1 mM uracil + 0.1 EDTA protect partially

638365

80

Saccharolobus shibatae

-

stable for at least 1 h

678368

80

[Bacillus] caldolyticus

P70881

10 min, inactivation

638370