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2.4.2.7: adenine phosphoribosyltransferase

This is an abbreviated version!
For detailed information about adenine phosphoribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.7

Reaction

AMP
+
diphosphate
=
adenine
+
5-phospho-alpha-D-ribose 1-diphosphate

Synonyms

adenine phosphoribosyl transferase, adenine phosphoribosylpyrophosphate transferase, adenine phosphoribosyltransferase, adenine phosphoribosyltransferase 2, adenione PRTase, adenosine phosphoribosyltransferase, adenylate pyrophosphorylase, adenylic pyrophosphorylase, AMP pyrophosphorylase, AMP-pyrophosphate phosphoribosyltransferase, AMP:pyrophosphate phospho-D-ribosyltransferase, APRT, APRT1, APRT2, APRTase, APRTh, apT, APT1, APT2, APT4, APT5, ApTR, FtAPRT, gpT-1, hAPRT, More, phosphoribosyltransferase, adenine, ScAPRT, SmAPRT1, Smp_054360, SSO2342, transphosphoribosidase, TtAPRT2, TTC1249, TTC1250, TTH1250, TTHA1614, TthAPRT, TthHB27APRT, TT_C1249, TT_C1250, type I PRT

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.7 adenine phosphoribosyltransferase

Reference

Reference on EC 2.4.2.7 - adenine phosphoribosyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tuttle, J.V.; Krenitsky, T.A.
Purine phosphoribosyltransferases from Leishmania donovani
J. Biol. Chem.
255
909-916
1980
Leishmania donovani
Manually annotated by BRENDA team
Flaks, J.G.; Erwin, M.J.; Buchanan, J.M.
Biosynthesis of the purines. XVI. The synthesis of adenosine 5'-phosphate and 5-amino-4-imidazolecarboxamide ribotide by a nucleotide pyrophosphorylase
J. Biol. Chem.
228
201-213
1957
Bos taurus
Manually annotated by BRENDA team
Lee, D.; Moffatt, B.A.
Purification and characterization of adenine phosphoribosyltransferase from Arabidopsis thaliana
Physiol. Plant.
87
483-492
1993
Arabidopsis thaliana
-
Manually annotated by BRENDA team
Hochstadt, J.
Adenine phosphoribosyltransferase from Escherichia coli
Methods Enzymol.
51
558-567
1978
Escherichia coli
Manually annotated by BRENDA team
Arnold, W.J.; Kelley, W.N.
Adenine phosphoribosyltransferase
Methods Enzymol.
51
568-574
1978
Homo sapiens
Manually annotated by BRENDA team
Groth, D.P.; Young, L.G.; Kenimer, J.G.
Adenine phosphoribosyltransferase from rat liver
Methods Enzymol.
51
574-580
1978
Rattus norvegicus
Manually annotated by BRENDA team
Holden, J.A.; Meredith, G.S.; Kelley, W.N.
Human adenine phosphoribosyltransferase. Affinity purification, subunit structure, amino acid composition, and peptide mapping
J. Biol. Chem.
254
6951-6955
1979
Homo sapiens
Manually annotated by BRENDA team
Thomas, C.B.; Arnold, W.J.; Kelley, W.N.
Human adenine phosphoribosyltransferase. Purification, subunit structure, and substrate specificity
J. Biol. Chem.
248
2529-2535
1973
Homo sapiens
Manually annotated by BRENDA team
Hirose, F.; Ashihara, H.
Adenine phosphoribosyltransferase of Catharanthus roseus cells: purification, properties and regulation
Z. Pflanzenphysiol.
110
135-145
1983
Catharanthus roseus
-
Manually annotated by BRENDA team
Chen, C.M.; Melitz, D.K.; Clough, F.W.
Metabolism of cytokinin: phosphoribosylation of cytokinin bases by adenine phosphoribosyltransferase from wheat germ
Arch. Biochem. Biophys.
214
634-641
1982
Triticum aestivum
Manually annotated by BRENDA team
Sin, I.L.; Finch, L.R.
Adenine phosphoribosyltransferase in Mycoplasma mycoides and Escherichia coli
J. Bacteriol.
112
439-444
1972
Escherichia coli, Mycoplasma mycoides
Manually annotated by BRENDA team
Kenimer, J.G.; Young, L.G.; Groth, D.P.
Purification and properties of rat liver adenine phosphoribosyltransferase
Biochim. Biophys. Acta
384
87-101
1975
Rattus norvegicus
Manually annotated by BRENDA team
Okada, G.; Kaneko, I.; Koyama, H.
Purification and characterization of adenine phosphoribosyltransferase from mouse mammary carcinoma FM3A cells in culture
Biochim. Biophys. Acta
884
304-310
1986
Mus musculus
Manually annotated by BRENDA team
Queen, S.A.; Vander Jagt, D.L.; Reyes, P.
Characterization of adenine phosphoribosyltransferase from the human malaria parasite, Plasmodium falciparum
Biochim. Biophys. Acta
996
160-165
1989
Plasmodium falciparum
Manually annotated by BRENDA team
Moffatt, B.A.; Somerville, C.R.
Purification of adenine phosphoribosyltransferase from Brassica juncea
Arch. Biochem. Biophys.
283
484-490
1990
Brassica juncea
Manually annotated by BRENDA team
Walter, R.D.; Koenigk, E.
Hypoxanthine-guanine phosphoribosyltransferase and adenine phosphoribosyltransferase from Plasmodium chabaudi, purification and properties
Tropenmed. Parasitol.
25
227-235
1974
Plasmodium chabaudi
Manually annotated by BRENDA team
Nagy, M.; Ribet, A.M.
Purification and comparative study of adenine and guanine phosphoribosyltransferases from Schizosaccharomyces pombe
Eur. J. Biochem.
77
77-85
1977
Schizosaccharomyces pombe
Manually annotated by BRENDA team
Montero, C.; Llorente, P.
Artemia purine phosphoribosyltransferases. Purification and characterization
Biochem. J.
275
327-334
1991
Artemia sp.
Manually annotated by BRENDA team
Wilson, J.M.; O'Toole, T.E.; Argos, P.; Shewach, D.S.; Daddona, P.E.; Kelley, W.N.
Human adenine phosphoribosyltransferase. Complete amino acid sequence of the erythrocyte enzyme
J. Biol. Chem.
261
13677-13683
1986
Homo sapiens
Manually annotated by BRENDA team
Bashor, C.; Denu, J.M.; Brennan, R.G.; Ullman, B.
Kinetic mechanism of adenine phosphoribosyltransferase from Leishmania donovani
Biochemistry
41
4020-4031
2002
Leishmania donovani
Manually annotated by BRENDA team
Gallois, R.; Prevot, J.C.; Clement, A.; Jacob, J.L.
Purification and characterization of an adenine phosphoribosyltransferase from rubber tree latex. Physiological implications
Plant Physiol. Biochem.
34
527-537
1996
Hevea brasiliensis
-
Manually annotated by BRENDA team
Phillips, C.L.; Ullman, B.; Brennan, R.G.; Hill, C.P.
Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani
EMBO J.
18
3533-3545
1999
Homo sapiens (P07741), Homo sapiens, Leishmania donovani (Q27679), Leishmania donovani
Manually annotated by BRENDA team
Sarver, A.E.; Wang, C.C.
The adenine phosphoribosyltransferase from Giardia lamblia has a unique reaction mechanism and unusual substrate binding properties
J. Biol. Chem.
277
39973-39980
2002
Giardia intestinalis (Q967M2), Giardia intestinalis
Manually annotated by BRENDA team
Shi, W.; Sarver, A.E.; Wang, C.C.; Tanaka, K.S.; Almo, S.C.; Schramm, V.L.
Closed site complexes of adenine phosphoribosyltransferase from Giardia lamblia reveal a mechanism of ribosyl migration
J. Biol. Chem.
277
39981-39988
2002
Giardia intestinalis (Q967M2), Giardia intestinalis
Manually annotated by BRENDA team
Alfonzo-Garcia, J.; Sahota, A.; Taylor, M.W.
Characterization of the adenine phosphoribosyltransferase from Saccharomyces cerevisiae
Adv. Exp. Med. Biol.
370
627-630
1994
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Allen, M.; Qin, W.; Moreau, F.; Moffatt, B.
Adenine phosphoribosyltransferase isoforms of Arabidopsis and their potential contributions to adenine and cytokinin metabolism
Physiol. Plant.
115
56-68
2002
Arabidopsis thaliana (P31166), Arabidopsis thaliana (Q42563), Arabidopsis thaliana (Q9LFP0), Arabidopsis thaliana (Q9SU38), Arabidopsis thaliana (Q9SUW2), Arabidopsis thaliana
Manually annotated by BRENDA team
Shi, W.; Tanaka, K.S.E.; Crother, T.R.; Taylor, M.W.; Almo, S.C.; Schramm, V.L.
Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae
Biochemistry
40
10800-10809
2001
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Allen, T.; Henschel, E.V.; Coons, T.; Cross, L.; Conley, J.; Ullman, B.
Purification and characterization of the adenine phosphoribosyltransferase and hypoxanthine-guanine phosphoribosyltransferase activities from Leishmania donovani
Mol. Biochem. Parasitol.
33
273-281
1989
Leishmania donovani
Manually annotated by BRENDA team
Silva, M.; Silva, C.H.; Iulek, J.; Thiemann, O.H.
Three-dimensional structure of human adenine phosphoribosyltransferase and its relation to DHA-urolithiasis
Biochemistry
43
7663-7671
2004
Homo sapiens (P07741), Homo sapiens
Manually annotated by BRENDA team
Silva, M.; Silva, C.H.; Iulek, J.; Oliva, G.; Thiemann, O.H.
Crystal structure of adenine phosphoribosyltransferase from Leishmania tarentolae: potential implications for APRT catalytic mechanism
Biochim. Biophys. Acta
1696
31-39
2004
Leishmania tarentolae
Manually annotated by BRENDA team
Sahota, A.; Chen, J.; Boyadijev, S.A.; Gault, M.H.; Tischfield, J.A.
Missense mutation in the adenine phosphoribosyl-transferase gene causing 2,8-dihydroxyadenine urolithiasis
Hum. Mol. Genet.
3
817-818
1994
Homo sapiens
Manually annotated by BRENDA team
Hidaka, Y.; Tarle, S.A.; Fujimori, S.; Kamatani, N.; Kelley, W.N.; Palella, T.D.
Human adenine phosphoribosyl-transferase deficiency. Demonstration of a single mutant allele common to the Japanese
J. Clin. InVest.
81
945-950
1988
Homo sapiens
Manually annotated by BRENDA team
Zarella-Boitz, J.M.; Rager, N.; Jardim, A.; Ullman, B.
Subcellular localization of adenine and xanthine phosphoribosyltransferases in Leishmania donovani
Mol. Biochem. Parasitol.
134
43-51
2004
Leishmania donovani
Manually annotated by BRENDA team
Crespillo, J.; Llorente, P.; Argomaniz, L.; Montero, C.
APRT from erythrocytes of HGPRT deficient patients: kinetic, regulatory and thermostability properties
Mol. Cell. Biochem.
254
359-363
2003
Homo sapiens
Manually annotated by BRENDA team
Taniguchi, A.; Tsuchida, S.; Kuno, S.; Mita, M.; Machida, T.; Ioritani, N.; Terai, C.; Yamanaka, H.; Kamatani, N.
Identification of two novel mutations in adenine phosphoribosyltransferase gene in patients with 2,8-dihydroxyadenine urolithiasis
Nucleosides Nucleotides Nucleic Acids
23
1141-1145
2004
Homo sapiens
Manually annotated by BRENDA team
Xing, Q.; Ru, Z.; Li, J.; Zhou, C.; Jin, D.; Sun, Y.; Wang, B.
Cloning a second form of adenine phosphoribosyl transferase gene (TaAPT2) from wheat and analysis of its association with thermo-sensitive genic male sterility (TGMS)
Plant Sci.
169
37-45
2005
Triticum aestivum (Q43199)
Manually annotated by BRENDA team
Di Pietro, V.; Perruzza, I.; Amorini, A.M.; Balducci, A.; Ceccarelli, L.; Lazzarino, G.; Barsotti, P.; Giardina, B.; Tavazzi, B.
Clinical, biochemical and molecular diagnosis of a compound homozygote for the 254 bp deletion-8 bp insertion of the APRT gene suffering from severe renal failure
Clin. Biochem.
40
73-80
2007
Homo sapiens, Homo sapiens (P07741)
Manually annotated by BRENDA team
Ambrozin, A.R.; Leite, A.C.; Silva, M.; Vieira, P.C.; Fernandes, J.B.; Thiemann, O.H.; da Silva, M.F.; Oliva, G.
Screening of Leishmania APRT enzyme inhibitors
Pharmazie
60
781-784
2005
Leishmania tarentolae
Manually annotated by BRENDA team
Zhou, C.J.; Li, J.; Zou, J.C.; Liang, F.S.; Ye, C.J.; Jin, D.M.; Weng, M.L.; Wang, B.
Cloning and characterization of a second form of the rice adenine phosphoribosyl transferase gene (OsAPT2) and its association with TGMS
Plant Mol. Biol.
60
365-376
2006
Arabidopsis thaliana (Q42563), Oryza sativa (Q84P57), Oryza sativa
Manually annotated by BRENDA team
Katahira, R.; Ashihara, H.
Role of adenosine salvage in wound-induced adenylate biosynthesis in potato tuber slices
Plant Physiol. Biochem.
44
551-555
2006
Solanum tuberosum (Q2V997), Solanum tuberosum
Manually annotated by BRENDA team
Rehse, P.H.; Tahirov, T.H.
Crystal structure of a purine/pyrimidine phosphoribosyltransferase-related protein from Thermus thermophilus HB8
Proteins
61
658-665
2005
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Manually annotated by BRENDA team
Wu, S.; Yu, Z.; Wang, F.; Li, W.; Yang, Q.; Ye, C.; Sun, Y.; Jin, D.; Zhao, J.; Wang, B.
Identification and characterization of a novel adenine phosphoribosyltransferase gene (ZmAPT2) from maize (Zea mays L.)
DNA Seq.
19
357-365
2008
Zea mays (Q6RYT6), Zea mays
Manually annotated by BRENDA team
Silva, C.H.; Silva, M.; Iulek, J.; Thiemann, O.H.
Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism
J. Biomol. Struct. Dyn.
25
589-597
2008
Homo sapiens (P07741), Homo sapiens
Manually annotated by BRENDA team
Alves, P.B.; Freire Filho, P.S.; Moraes, V.R.; Blank, A.F.; de Carvalho Filho, J.L.; Arrigoni-Blank, M.d.; Oliva, G.; Thiemann, O.H.
Chemical composition of essential oil from seven Ocimum basilicum L. Accessions, Brine shrimp lethality bioassay and inhibitory activities against GAPDH and APRT
J. Essent. Oil Res.
19
89-92
2007
Leishmania tarentolae (O77103)
Manually annotated by BRENDA team
Ea, H.K.; Bardin, T.; Jinnah, H.A.; Aral, B.; Liote, F.; Ceballos-Picot, I.
Severe gouty arthritis and mild neurologic symptoms due to F199C, a newly identified variant of the hypoxanthine guanine phosphoribosyltransferase
Arthritis Rheum.
60
2201-2204
2009
Homo sapiens
Manually annotated by BRENDA team
Ceballos-Picot, I.; Mockel, L.; Potier, M.C.; Dauphinot, L.; Shirley, T.L.; Torero-Ibad, R.; Fuchs, J.; Jinnah, H.A.
Hypoxanthine-guanine phosphoribosyl transferase regulates early developmental programming of dopamine neurons: implications for Lesch-Nyhan disease pathogenesis
Hum. Mol. Genet.
18
2317-2327
2009
Homo sapiens
Manually annotated by BRENDA team
Iwaki, T.; Kusaka, T.; Ohashi, I.; Nishida, T.; Imai, T.; Itoh, S.
Two families with compound heterozygosity for adenine phosphoribosyltransferase deficiency
Pediatr. Nephrol.
25
1173-1176
2010
Homo sapiens
Manually annotated by BRENDA team
Baranowska-Bosiacka, I.; Dziedziejko, V.; Safranow, K.; Gutowska, I.; Marchlewicz, M.; Dolegowska, B.; Rac, M.E.; Wiszniewska, B.; Chlubek, D.
Inhibition of erythrocyte phosphoribosyltransferases (APRT and HPRT) by Pb2+: a potential mechanism of lead toxicity
Toxicology
259
77-83
2009
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Parker, W.B.; Allan, P.W.; Waud, W.R.; Hong, J.S.; Sorscher, E.J.
Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase
Cancer Gene Ther.
18
390-398
2011
Homo sapiens
Manually annotated by BRENDA team
Boitz, J.M.; Ullman, B.
Amplification of adenine phosphoribosyltransferase suppresses the conditionally lethal growth and virulence phenotype of Leishmania donovani mutants lacking both hypoxanthine-guanine and xanthine phosphoribosyltransferases
J. Biol. Chem.
285
18555-18564
2010
Leishmania donovani
Manually annotated by BRENDA team
Hansen, M.R.; Jensen, K.S.; Rasmussen, M.S.; Christoffersen, S.; Kadziola, A.; Jensen, K.F.
Specificities and pH profiles of adenine and hypoxanthine-guanine-xanthine phosphoribosyltransferases (nucleotide synthases) of the thermoacidophile archaeon Sulfolobus solfataricus
Extremophiles
18
179-187
2014
Saccharolobus solfataricus, Saccharolobus solfataricus P2
Manually annotated by BRENDA team
Jensen, K.F.; Hansen, M.R.; Jensen, K.S.; Christoffersen, S.; Poulsen, J.C.; Molgaard, A.; Kadziola, A.
Adenine phosphoribosyltransferase from Sulfolobus solfataricus is an enzyme with unusual kinetic properties and a crystal structure that suggests it evolved from a 6-oxopurine phosphoribosyltransferase
Biochemistry
54
2323-2334
2015
Saccharolobus solfataricus (Q97W95), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q97W95), Saccharolobus solfataricus P2
Manually annotated by BRENDA team
Stuer-Lauridsen, B.; Nygaard, P.
Purine salvage in two halophilic archaea: characterization of salvage pathways and isolation of mutants resistant to purine analogs
J. Bacteriol.
180
457-463
1998
Halobacterium salinarum, Haloferax volcanii
Manually annotated by BRENDA team
Zhang, X.; Chen, Y.; Lin, X.; Hong, X.; Zhu, Y.; Li, W.; He, W.; An, F.; Guo, H.
Adenine phosphoribosyl transferase 1 is a key enzyme catalyzing cytokinin conversion from nucleobases to nucleotides in Arabidopsis
Mol. Plant
6
1661-1672
2013
Arabidopsis thaliana (P31166), Arabidopsis thaliana (Q42563), Arabidopsis thaliana (Q9LFP0), Arabidopsis thaliana (Q9SU38)
Manually annotated by BRENDA team
Harris, L.D.; Harijan, R.K.; Ducati, R.G.; Evans, G.B.; Hirsch, B.M.; Schramm, V.L.
Synthesis of bis-phosphate iminoaltritol enantiomers and structural characterization with adenine phosphoribosyltransferase
ACS Chem. Biol.
13
152-160
2018
Saccharomyces cerevisiae (P49435), Saccharomyces cerevisiae, Saccharomyces cerevisiae ATCC 204508 (P49435)
Manually annotated by BRENDA team
Fateev, I.V.; Sinitsina, E.V.; Bikanasova, A.U.; Kostromina, M.A.; Tuzova, E.S.; Esipova, L.V.; Muravyova, T.I.; Kayushin, A.L.; Konstantinova, I.D.; Esipov, R.S.
Thermophilic phosphoribosyltransferases Thermus thermophilus HB27 in nucleotide synthesis
Beilstein J. Org. Chem.
14
3098-3105
2018
Thermus thermophilus (Q72I82)
Manually annotated by BRENDA team
Del Arco, J.; Martinez, M.; Donday, M.; Clemente-Suarez, V.; Fernandez-Lucas, J.
Cloning, expression and biochemical characterization of xanthine and adenine phosphoribosyltransferases from Thermus thermophilus HB8
Biocatal. Biotransform.
36
216-223
2018
Thermus thermophilus (Q5SHW6), Thermus thermophilus DSM 579 (Q5SHW6), Thermus thermophilus ATCC 27634 (Q5SHW6)
-
Manually annotated by BRENDA team
Arco, J.D.; Perez, E.; Naitow, H.; Matsuura, Y.; Kunishima, N.; Fernandez-Lucas, J.
Structural and functional characterization of thermostable biocatalysts for the synthesis of 6-aminopurine nucleoside-5-monophospate analogues
Biores. Technol.
276
244-252
2019
Thermus thermophilus (Q5SHW6), Thermus thermophilus DSM 579 (Q5SHW6), Thermus thermophilus ATCC 27634 (Q5SHW6)
Manually annotated by BRENDA team
Huyet, J.; Ozeir, M.; Burgevin, M.C.; Pinson, B.; Chesney, F.; Remy, J.M.; Siddiqi, A.R.; Lupoli, R.; Pinon, G.; Saint-Marc, C.; Gibert, J.F.; Morales, R.; Ceballos-Picot, I.; Barouki, R.; Daignan-Fornier, B.; Olivier-Bandini, A.; Auge, F.; Nioche, P.
Structural insights into the forward and reverse enzymatic reactions in human adenine phosphoribosyltransferase
Cell Chem. Biol.
25
666-676.e4
2018
Homo sapiens (P07741), Homo sapiens
Manually annotated by BRENDA team
Sinitsyna, E.; Timofeev, V.; Tuzova, E.; Kostromina, M.; Murav'eva, T.; Esipov, R.; Kuranova, I.
Crystallization and preliminary X-ray diffraction study of recombinant adenine phosphoribosyltransferase from the thermophilic bacterium Thermus thermophilus strain HB27
Crystallogr. Rep.
62
580-583
2017
Thermus thermophilus (Q72I82), Thermus thermophilus DSM 7039 (Q72I82), Thermus thermophilus ATCC BAA-163 (Q72I82)
-
Manually annotated by BRENDA team
Pavithra, G.C.; Ramagopal, U.A.
Crystal structures of APRT from Francisella tularensis - an N-H-N hydrogen bond imparts adenine specificity in adenine phosphoribosyltransferases
FEBS J.
285
2306-2318
2018
Francisella tularensis subsp. tularensis (Q5NII9), Francisella tularensis subsp. tularensis Schu 4 (Q5NII9)
Manually annotated by BRENDA team
Tomita, T.; Matsushita, H.; Yoshida, A.; Kosono, S.; Yoshida, M.; Kuzuyama, T.; Nishiyama, M.
Glutamate dehydrogenase from Thermus thermophilus is activated by AMP and leucine as a complex with catalytically inactive adenine phosphoribosyltransferase homolog
J. Bacteriol.
201
e00710-18
2019
Thermus thermophilus (Q72I82), Thermus thermophilus (Q72I83), Thermus thermophilus, Thermus thermophilus DSM 7039 (Q72I82), Thermus thermophilus DSM 7039 (Q72I83), Thermus thermophilus ATCC BAA-163 (Q72I82), Thermus thermophilus ATCC BAA-163 (Q72I83)
Manually annotated by BRENDA team
Ozeir, M.; Huyet, J.; Burgevin, M.C.; Pinson, B.; Chesney, F.; Remy, J.M.; Siddiqi, A.R.; Lupoli, R.; Pinon, G.; Saint-Marc, C.; Gibert, J.F.; Morales, R.; Ceballos-Picot, I.; Barouki, R.; Daignan-Fornier, B.; Olivier-Bandini, A.; Auge, F.; Nioche, P.
Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction
J. Biol. Chem.
294
11980-11991
2019
Homo sapiens (P07741), Homo sapiens
Manually annotated by BRENDA team
Zayats, E.A.; Timofeev, V.I.; Kostromina, M.A.; Esipov, R.S.
An explanation for the narrow carbohydrate substrate specificity of adenine phosphoribosyltransferase from Thermus thermophilus from the model of the enzyme, substrate, and magnesium cation cofactor complex
J. Biomol. Struct. Dyn.
37
4460-4464
2019
Thermus thermophilus (Q72I82), Thermus thermophilus, Thermus thermophilus DSM 7039 (Q72I82), Thermus thermophilus ATCC BAA-163 (Q72I82)
Manually annotated by BRENDA team
Garcia-Huertas, P.; Mejia-Jaramillo, A.M.; Gonzalez, L.; Triana-Chavez, O.
Transcriptome and functional genomics reveal the participation of adenine phosphoribosyltransferase in Trypanosoma cruzi resistance to benznidazole
J. Cell. Biochem.
118
1936-1945
2017
Trypanosoma cruzi, Trypanosoma cruzi MHOM, Trypanosoma cruzi DA (TcI), Trypanosoma cruzi COL
Manually annotated by BRENDA team
Zeraik, A.E.; Balasco Serrao, V.H.; Romanello, L.; Torini, J.R.; Cassago, A.; DeMarco, R.; Pereira, H.D.
Schistosoma mansoni displays an adenine phosphoribosyltransferase preferentially expressed in mature female gonads and vitelaria
Mol. Biochem. Parasitol.
214
82-86
2017
Schistosoma mansoni (G4VQJ4), Schistosoma mansoni
Manually annotated by BRENDA team
Esipov, R.; Timofeev, V.; Sinitsyna, E.; Tuzova, E.; Esipova, L.; Kostromina, M.; Kuranova, I.; Miroshnikov, A.
Three-dimensional structure of recombinant adenine phosphoribosyltransferase from thermophilic bacterial strain Thermus thermophilus HB27
Russ. J. Bioorg. Chem.
44
504-510
2018
Thermus thermophilus (Q72I82), Thermus thermophilus DSM 7039 (Q72I82), Thermus thermophilus ATCC BAA-163 (Q72I82)
-
Manually annotated by BRENDA team