2.4.2.7: adenine phosphoribosyltransferase

This is an abbreviated version!
For detailed information about adenine phosphoribosyltransferase, go to the full flat file.

Reaction

Synonyms

adenine phosphoribosyl transferase, adenine phosphoribosylpyrophosphate transferase, adenine phosphoribosyltransferase, adenine phosphoribosyltransferase 2, adenione PRTase, adenosine phosphoribosyltransferase, adenylate pyrophosphorylase, adenylic pyrophosphorylase, AMP pyrophosphorylase, AMP-pyrophosphate phosphoribosyltransferase, AMP:pyrophosphate phospho-D-ribosyltransferase, APRT, APRT1, APRT2, APRTase, APRTh, apT, APT1, APT2, APT4, APT5, ApTR, FtAPRT, gpT-1, hAPRT, More, phosphoribosyltransferase, adenine, ScAPRT, SmAPRT1, Smp_054360, SSO2342, transphosphoribosidase, TtAPRT2, TTC1249, TTC1250, TTH1250, TTHA1614, TthAPRT, TthHB27APRT, TT_C1249, TT_C1250, type I PRT

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.7 adenine phosphoribosyltransferase

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Results	in table
5	Activating Compound
33808	AA Sequence
3	Application
1	CAS Registry Number
27	Cloned(Commentary)
15	Crystallization (Commentary)
1379	Disease/ Diagnostics
9	Expression
67	General Information
11	General Stability
1	IC50 Value
121	Inhibitors
10	kcat/KM [mM/s]
36	Ki Value [mM]
94	KM Value [mM]
9	Localization
77	Metals/Ions
36	Molecular Weight [Da]
46	Natural Substrates/ Products (Substrates)
257	Organism
9	Pathway
79	PDB ID
41	pH Optimum
7	pH Range
3	pI Value
45	Protein Variants
40	Purification (Commentary)
12	Reaction
1	Reaction Type
92	Reference
55	Source Tissue
36	Specific Activity [micromol/min/mg]
13	Storage Stability
202	Substrates and Products (Substrate)
46	Subunits
146	Synonyms
1	Systematic Name
34	Temperature Optimum [°C]
1	Temperature Range [°C]
28	Temperature Stability [°C]
30	Turnover Number [1/s]

General Stability

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General Stability on EC 2.4.2.7 - adenine phosphoribosyltransferase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

5-phospho-alpha-D-ribose 1-diphosphate stabilizes Mycoplasma mycoides enzyme markedly

Mycoplasma mycoides

-

638155

ammonium sulfate, 1 M, partially protects against inactivation during storage

Homo sapiens

-

638151

bovine serum albumin or adenine stabilizes Mycoplasma mycoides enzyme slightly

Mycoplasma mycoides

-

638155

dialysis against 20 mM Tris-HCl, pH 7.5, 20 mM (NH4)2SO4 + 5 mM 2-mercaptoethanol inactivates

Rattus norvegicus

-

638156

dithiothreitol, 10 mM, or dimethylsulfoxide, 5%, or 5-phospho-alpha-D-ribose 1-diphosphate, 1 mM, protects against inactivation during storage

Homo sapiens

-

638151

freezing and thawing have little effect on E. coli enzyme, but inactivate Mycoplasma mycoides enzyme

2 entries

inactivation by isoelectric focusing

Leishmania donovani

-

638004

instability after calcium phosphate gel treatment

Escherichia coli

-

638147

Mg2+ stabilizes

Rattus norvegicus

-

638156

unstable in absence of Mg2+ and glycerol, loss 0f 70% activity during gel filtration

Arabidopsis thaliana

-

638146

freezing and thawing have little effect on E. coli enzyme, but inactivate Mycoplasma mycoides enzyme

Escherichia coli

-

638155

freezing and thawing have little effect on E. coli enzyme, but inactivate Mycoplasma mycoides enzyme

Mycoplasma mycoides

-

638155