2.4.2.53: undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
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For detailed information about undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, go to the full flat file.
Reaction
Synonyms
ArnC, EC 2.7.8.30, EptA, lipopolysaccharide export system protein LptA, LptA, NMB1638, PA14_39020, PmrF, polymyxin resistance protein F
ECTree
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3982 | AA Sequence |
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3 | General Information |
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Expression
Expression on EC 2.4.2.53 - undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
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low Mg2+/Ca2+ concentration of 1 mM and a pH decrease from 8 to 6 both induce polymyxin resistance. Transcription of the pmrF operon in Yersinia pseudotuberculosis increases accordingly, by a factor of 7 and 2.5 for the Mg2+/Ca2+ ion starvation and acidic pH conditions, respectively
pmrF expression is independent of polymyxin resistance proteins PmrA-PmrB in Yersinia pseudotuberculosis, with the response regulator PhoP interacting directly with the pmrF operon promoter region