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2.4.2.46: galactan 5-O-arabinofuranosyltransferase

This is an abbreviated version!
For detailed information about galactan 5-O-arabinofuranosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.46

Reaction

3 trans,octacis-decaprenylphospho-beta-D-arabinofuranose +

[beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
= 3 trans,octacis-decaprenyl phosphate +
[beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]2-[[beta-D-arabinofuranosyl-(1->5)]-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]-[beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]-[[beta-D-arabinofuranosyl-(1->5)]-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]-[beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]-[[beta-D-arabinofuranosyl-(1->5)]-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]-[beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]7-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol

Synonyms

AftA, aftB, AftD, alpha(1->5) AraT, alpha1(1->5) arabinofuranosyltransferase, arabinofuranosyltransferase, arabinofuranosyltransferase A, Araf T, ArafT, ArAT, Rv3792

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.46 galactan 5-O-arabinofuranosyltransferase

Reference

topprint

Reference on EC 2.4.2.46 - galactan 5-O-arabinofuranosyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Alderwick, L.J.; Seidel, M.; Sahm, H.; Besra, G.S.; Eggeling, L.
Identification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosis
J. Biol. Chem.
281
15653-15661
2006
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Manually annotated by BRENDA team
Jankute, M.; Byng, C.V.; Alderwick, L.J.; Besra, G.S.
Elucidation of a protein-protein interaction network involved in Corynebacterium glutamicum cell wall biosynthesis as determined by bacterial two-hybrid analysis
Glycoconj. J.
31
475-483
2014
Corynebacterium glutamicum (Q8NTW4)
Manually annotated by BRENDA team
Safi, H.; Lingaraju, S.; Amin, A.; Kim, S.; Jones, M.; Holmes, M.; McNeil, M.; Peterson, S.N.; Chatterjee, D.; Fleischmann, R.; Alland, D.
Evolution of high-level ethambutol-resistant tuberculosis through interacting mutations in decaprenylphosphoryl-alpha-D-arabinose biosynthetic and utilization pathway genes
Nat. Genet.
45
1190-1197
2013
Mycobacterium tuberculosis (P9WN03), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WN03)
Manually annotated by BRENDA team
Jankute, M.; Alderwick, L.J.; Noack, S.; Veerapen, N.; Nigou, J.; Besra, G.S.
Disruption of mycobacterial AftB results in complete loss of terminal beta(1 -> 2) arabinofuranose residues of lipoarabinomannan
ACS Chem. Biol.
12
183-190
2017
Mycolicibacterium smegmatis, Mycolicibacterium smegmatis mc2155
Manually annotated by BRENDA team
Alderwick, L.; Birch, H.; Krumbach, K.; Bott, M.; Eggeling, L.; Besra, G.
AftD functions as an alpha1->5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core
Cell Surf.
1
2-14
2018
Corynebacterium glutamicum
-
Manually annotated by BRENDA team