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2.4.2.4: thymidine phosphorylase

This is an abbreviated version!
For detailed information about thymidine phosphorylase, go to the full flat file.

Word Map on EC 2.4.2.4

Reaction

thymidine
+
phosphate
=
thymine
+
2-deoxy-alpha-D-ribose 1-phosphate

Synonyms

angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase, animal growth regulators, blood platelet-derived endothelial cell growth factors, blood platelet-derived endothelial cell growth factor, deoA, deoxythymidine phosphorylase, dthdpase, EC 2.4.2.23, gliostatin, gliostatins, GLS, HTP, More, PD-ECGF, PD-ECGF/TP, PD-ECGF/TP platelet-derived endothelial cell growth factor, PDECGF, phosphorylase, thymidine, platelet derived endothelial cell growth factor, platelet derived endothelial cell grwoth factor, platelet derived-endothelial cell growth factor, platelet-derived endothelial cell growth factor, platelet-derived endothelial cell growth factor/thymidine phosphorylase, platelet-derived endotherial cell growth factor, ppnP, pynpase, pyrimidine deoxynucleoside phosphorylase, pyrimidine nucleoside phosphorylase, pyrimidine phosphorylase, pyrimidine/purine nucleoside phosphorylase, TDRPASE, ThdPase, thymidine phosphorylase, thymidine Pi deoxyribosyltransferase, thymidine-orthophosphate deoxyribosyltransferase, thymidine:orthophosphate deoxy-D-ribosyltransferase, Tpase, TYMP

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.4 thymidine phosphorylase

Turnover Number

Turnover Number on EC 2.4.2.4 - thymidine phosphorylase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.45
1-(2',6'-dideoxy-alpha-L-lyxo-hexafuranosyl)thymine
25°C, pH 6.5
0.45
1-(2',6'-dideoxy-alpha-L-lyxohexafuranosyl)thymine
in 50 mM potassium phosphate buffer (pH 6.5), at 25°C
0.1
1-(2',6'-dideoxy-beta-D-ribo-hexafuranosyl)thymine
25°C, pH 6.5
0.1 - 0.6
1-(2',6'-dideoxy-beta-D-ribohexafuranosyl)thymine
35
2'-deoxyuridine
-
1.1
3'-amino-3'-deoxythymidine
0.4
3'-deoxy-2',3'-didehydrothymidine
63
4-thiothymidine
0.58
5'-amino-5'-deoxythymidine
1.7
5'-chloro-5'-deoxythymidine
-
260
5'-Deoxythymidine
2.88 - 20
5-nitro-2'-deoxyuridine
0.157 - 1770
thymidine