2.4.2.36: NAD+-diphthamide ADP-ribosyltransferase
This is an abbreviated version!
For detailed information about NAD+-diphthamide ADP-ribosyltransferase, go to the full flat file.
Word Map on EC 2.4.2.36
-
2.4.2.36
-
camp
-
cyclase
-
vibrio
-
mucosal
-
pertussis
-
adp-ribosylation
-
adenylate
-
forskolin
-
retrograde
-
gm1
-
ganglioside
-
aeruginosa
-
enterotoxin
-
iga
-
agonist
-
tracer
-
dorsal
-
prostaglandin
-
heat-labile
-
intranasal
-
dibutyryl
-
afferent
-
isoproterenol
-
adenylyl
-
g-proteins
-
innervation
-
gtp-binding
-
diphtheria
-
immunotoxins
-
anterograde
-
b-subunits
-
rostrally
-
toxigenic
-
ribosylation
-
pilus
-
toxin-induced
-
toxin-sensitive
-
pyrogenic
-
toxoid
-
8-bromo-camp
-
diarrheal
-
antitoxin
-
ventrolateral
-
peyer
-
exoenzyme
-
enterotoxigenic
-
gppnhp
-
preganglionic
-
drug development
-
wga-hrp
-
parabrachial
-
medicine
-
diagnostics
- 2.4.2.36
- camp
- cyclase
- vibrio
- mucosal
- pertussis
-
adp-ribosylation
- adenylate
- forskolin
-
retrograde
- gm1
- ganglioside
- aeruginosa
- enterotoxin
- iga
- agonist
-
tracer
-
dorsal
- prostaglandin
-
heat-labile
-
intranasal
-
dibutyryl
-
afferent
- isoproterenol
-
adenylyl
- g-proteins
-
innervation
-
gtp-binding
- diphtheria
- immunotoxins
-
anterograde
-
b-subunits
-
rostrally
-
toxigenic
-
ribosylation
- pilus
-
toxin-induced
-
toxin-sensitive
-
pyrogenic
- toxoid
- 8-bromo-camp
-
diarrheal
- antitoxin
-
ventrolateral
-
peyer
-
exoenzyme
-
enterotoxigenic
-
gppnhp
-
preganglionic
- drug development
-
wga-hrp
-
parabrachial
- medicine
- diagnostics
Reaction
Synonyms
(adenosine diphosphoribose)transferase, nicotinamide adenine dinucleotide-elongation factor 2, ADP-ribosyltransferase, cholera toxin, cholix, cholix toxin, chxA, CTB, diphthamide-specific ADPRT, diphthamide-specific mono-ADP-ribosylating toxin, EHI 155600, EhToxin-l, EhToxin-like, ExoA, ExoA(c), exotoxin A, mono(ADPribosyl)transferase, mono-ADP-ribosyltransferase, NAD(+)-diphthamide ADP-ribosyltransferase, NAD-diphthamide ADP-ribosyltransferase, NAD-diphthamide ADP-ribosyltransferase NAD-elongation factor 2 ADP-ribosyltransferase, NAD:elongation factor 2-adenosine diphosphate ribose-transferase
ECTree
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Reference
Reference on EC 2.4.2.36 - NAD+-diphthamide ADP-ribosyltransferase
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Lee, H.; Iglewski, W.J.
Cellular ADP-ribosyltransferase with the same mechanism of action as diphtheria toxin and Pseudomonas toxin A
Proc. Natl. Acad. Sci. USA
81
2703-2707
1984
Bos taurus, Mesocricetus auratus, Pseudomonas aeruginosa
Sanai, Y.; Morihara, K.; Tsuzuki, H.; Homma, J.Y.; Kato, I.
Proteolytic cleavage of exotoxin A from Pseudomonas aeruginosa: formation of an ADP-ribosyltransferase active fragment by the action of Pseudomonas elastase
FEBS Lett.
120
131-134
1980
Pseudomonas aeruginosa
Leppla, S.H.; Martin, O.C.; Muehl, L.A.
The exotoxin P. aeruginosa: a proenzyme having an unusual mode of activation
Biochem. Biophys. Res. Commun.
81
532-538
1978
Pseudomonas aeruginosa
Armstrong, S.; Merrill, A.R.
Toward the elucidation of the catalytic mechanism of the mono-ADP-ribosyltransferase activity of Pseudomonas aeruginosa exotoxin A
Biochemistry
43
183-194
2004
Pseudomonas aeruginosa
Zhang, Y.; Liu, S.; Lajoie, G.; Merrill, A.R.
The role of the diphthamide-containing loop within eukaryotic elongation factor 2 in ADP-ribosylation by Pseudomonas aeruginosa exotoxin A
Biochem. J.
413
163-174
2008
Pseudomonas aeruginosa
Jorgensen, R.; Wang, Y.; Visschedyk, D.; Merrill, A.R.
The nature and character of the transition state for the ADP-ribosyltransferase reaction
EMBO Rep.
9
802-809
2008
Pseudomonas aeruginosa (P11439), Pseudomonas aeruginosa
Zhang, G.
Design, synthesis, and evaluation of bisubstrate analog inhibitors of cholera toxin
Bioorg. Med. Chem. Lett.
18
3724-3727
2008
Vibrio cholerae serotype O1
Feng, B.S.; Zheng, P.Y.; Chen, X.; Liao, X.Q.; Yang, P.C.
Investigation of the role of cholera toxin in assisting the initiation of the antigen-specific Th2 response
Immunol. Invest.
37
782-797
2008
Vibrio cholerae serotype O1
Jang, H.; Kim, H.S.; Kim, J.A.; Seo, J.H.; Carbis, R.
Improved purification process for cholera toxin and its application to the quantification of residual toxin in cholera vaccines
J. Microbiol. Biotechnol.
19
108-112
2009
Vibrio cholerae serotype O1, Vibrio cholerae serotype O1 569B
Gong, Z.; Long, X.; Pan, L.; Le, Y.; Liu, Q.; Wang, S.; Guo, J.; Xiao, B.; Zhou, M.; Mei, D.
Cloning, expression, purification and characterization of the cholera toxin B subunit and triple glutamic acid decarboxylase epitopes fusion protein in Escherichia coli
Protein Expr. Purif.
191
191-197
2009
Vibrio cholerae serotype O1
Fieldhouse, R.J.; Jurgensen, R.; Lugo, M.R.; Merrill, A.R.
The 1.8 A cholix toxin crystal structure in complex with NAD+ and evidence for a new kinetic model
J. Biol. Chem.
287
21176-21188
2012
Vibrio cholerae serotype O1
Lugo, M.R.; Merrill, A.R.
The father, son and cholix toxin: The third member of the dt group mono-ADP-ribosyltransferase toxin family
Toxins
7
2757-2772
2015
Pseudomonas aeruginosa (P11439), Pseudomonas aeruginosa, Vibrio cholerae (Q5EK40), Vibrio cholerae
Avila, E.E.; Rodriguez, O.I.; Marquez, J.A.; Berghuis, A.M.
An Entamoeba histolytica ADP-ribosyl transferase from the diphtheria toxin family modifies the bacterial elongation factor Tu
Mol. Biochem. Parasitol.
207
68-74
2016
Entamoeba histolytica (C4LWB1), Entamoeba histolytica
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