2.4.2.36: NAD+-diphthamide ADP-ribosyltransferase

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For detailed information about NAD+-diphthamide ADP-ribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.36

2.4.2.36

camp

cyclase

vibrio

mucosal

pertussis

adp-ribosylation

adenylate

forskolin

retrograde

gm1

ganglioside

aeruginosa

enterotoxin

iga

agonist

tracer

dorsal

prostaglandin

heat-labile

intranasal

dibutyryl

afferent

isoproterenol

adenylyl

g-proteins

innervation

gtp-binding

diphtheria

immunotoxins

anterograde

b-subunits

rostrally

toxigenic

ribosylation

pilus

toxin-induced

toxin-sensitive

pyrogenic

toxoid

8-bromo-camp

diarrheal

antitoxin

ventrolateral

peyer

exoenzyme

enterotoxigenic

gppnhp

preganglionic

drug development

wga-hrp

parabrachial

medicine

diagnostics

Reaction

diphthamide-[translation elongation factor 2]

N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2]

Synonyms

(adenosine diphosphoribose)transferase, nicotinamide adenine dinucleotide-elongation factor 2, ADP-ribosyltransferase, cholera toxin, cholix, cholix toxin, chxA, CTB, diphthamide-specific ADPRT, diphthamide-specific mono-ADP-ribosylating toxin, EHI 155600, EhToxin-l, EhToxin-like, ExoA, ExoA(c), exotoxin A, mono(ADPribosyl)transferase, mono-ADP-ribosyltransferase, NAD(+)-diphthamide ADP-ribosyltransferase, NAD-diphthamide ADP-ribosyltransferase, NAD-diphthamide ADP-ribosyltransferase NAD-elongation factor 2 ADP-ribosyltransferase, NAD:elongation factor 2-adenosine diphosphate ribose-transferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.2 Pentosyltransferases

2.4.2.36 NAD+-diphthamide ADP-ribosyltransferase

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Results	in table
8	Activating Compound
41	AA Sequence
4	Application
1	CAS Registry Number
4	Cloned(Commentary)
1	Cofactor
4	Crystallization (Commentary)
2	General Information
9	IC50 Value
31	Inhibitors
8	Ki Value [mM]
41	KM Value [mM]
5	Localization
2	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
18	Organism
42	PDB ID
3	pH Optimum
1	Posttranslational Modification
45	Protein Variants
6	Purification (Commentary)
1	Reaction
2	Reaction Type
18	Reference
4	Source Tissue
21	Substrates and Products (Substrate)
5	Subunits
30	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
84	Turnover Number [1/s]

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Application on EC 2.4.2.36 - NAD+-diphthamide ADP-ribosyltransferase

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diagnostics

2 entries

drug development

Pseudomonas aeruginosa

P11439

more potent therapeutics for treatment of bacterial diseases and infections through understanding of ADPRT reaction meachanism

692077

medicine

Vibrio cholerae serotype O1

therapy for autoimmune diabetes with glutamic acid decarboxylase 65 as autoantigen combined with cholera toxin B subunit as adjuvans lowering the number of antigens needed for autoimmune suppression, oral application for 5 weeks reduces insulitis of pancreas in mouse model

701050