2.4.2.3: uridine phosphorylase

This is an abbreviated version!
For detailed information about uridine phosphorylase, go to the full flat file.

Word Map on EC 2.4.2.3

2.4.2.3

pyrimidine

nucleoside

thymidine

uracil

5-fluorouracil

phosphorolysis

salvage

orotate

phosphoribosyltransferase

phosphorylases

thymidylate

fluoropyrimidine

udp

5'-deoxy-5-fluorouridine

5-fluoro-2'-deoxyuridine

dihydropyrimidine

acyclonucleoside

5-fluorouridine

ribose-1-phosphate

capecitabine

5-methyluridine

dthdpase

fdurd

orotidine

dihydrouracil

uridine-cytidine

mete

diagnostics

medicine

synthesis

drug development

Reaction

Synonyms

apUP, EC 2.4.2.23, L-UrdPase, More, PcUP1, PcUP2, phosphorylase, uridine, pynpase, pyrimidine nucleoside phosphorylase, pyrimidine phosphorylase, pyrimidine/purine nucleoside phosphorylase, StUPh, udp, UDRPase , UP type 1, UP1, UP2, uPA, UPase, UPase-2, UPb, UPH, UPP1, UPP2, UrdPase, uridine phosphorylase, uridine phosphorylase 1, uridine phosphorylase-1, uridine phosphorylase-2, uridine:orthophosphate alpha-D-ribosyltransferase, VchUPh

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.2 Pentosyltransferases

2.4.2.3 uridine phosphorylase

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Results	in table
5	Activating Compound
5766	AA Sequence
9	Application
1	CAS Registry Number
32	Cloned(Commentary)
31	Crystallization (Commentary)
354	Disease/ Diagnostics
7	Expression
19	General Information
4	General Stability
127	Inhibitors
8	kcat/KM [mM/s]
39	Ki Value [mM]
85	KM Value [mM]
10	Localization
2	Metals/Ions
29	Molecular Weight [Da]
41	Natural Substrates/ Products (Substrates)
667	Organism
8	Pathway
483	PDB ID
23	pH Optimum
7	pH Range
1	pH Stability
78	Protein Variants
46	Purification (Commentary)
18	Reaction
3	Reaction Type
127	Reference
1	Renatured (Commentary)
86	Source Tissue
20	Specific Activity [micromol/min/mg]
6	Storage Stability
200	Substrates and Products (Substrate)
35	Subunits
81	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
1	Temperature Range [°C]
8	Temperature Stability [°C]
6	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 2.4.2.3 - uridine phosphorylase

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Klebsiella aerogenes

1 month, 20% loss of activity

489668

2 entries

Escherichia coli

aglycone substrates, nucleoside substrates, phosphate or pentose 1-phosphate ester substrates stabilize against heat inactivation

638452

Escherichia coli

1 h, 3.7% residual activity for wild-type, 80.2% residual activity for mutant UPL8

723000

Aeropyrum pernix

Q9YA34

after incubation for 60 min at 90 °C, the enzyme remains 100% active

726781