2.4.2.3: uridine phosphorylase

This is an abbreviated version!
For detailed information about uridine phosphorylase, go to the full flat file.

Word Map on EC 2.4.2.3

2.4.2.3

pyrimidine

nucleoside

thymidine

uracil

5-fluorouracil

phosphorolysis

salvage

orotate

phosphoribosyltransferase

phosphorylases

thymidylate

fluoropyrimidine

udp

5'-deoxy-5-fluorouridine

5-fluoro-2'-deoxyuridine

dihydropyrimidine

acyclonucleoside

5-fluorouridine

ribose-1-phosphate

capecitabine

5-methyluridine

dthdpase

fdurd

orotidine

dihydrouracil

uridine-cytidine

mete

diagnostics

medicine

synthesis

drug development

Reaction

Synonyms

apUP, EC 2.4.2.23, L-UrdPase, More, PcUP1, PcUP2, phosphorylase, uridine, pynpase, pyrimidine nucleoside phosphorylase, pyrimidine phosphorylase, pyrimidine/purine nucleoside phosphorylase, StUPh, udp, UDRPase , UP type 1, UP1, UP2, uPA, UPase, UPase-2, UPb, UPH, UPP1, UPP2, UrdPase, uridine phosphorylase, uridine phosphorylase 1, uridine phosphorylase-1, uridine phosphorylase-2, uridine:orthophosphate alpha-D-ribosyltransferase, VchUPh

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.2 Pentosyltransferases

2.4.2.3 uridine phosphorylase

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Results	in table
5	Activating Compound
5766	AA Sequence
9	Application
1	CAS Registry Number
32	Cloned(Commentary)
31	Crystallization (Commentary)
354	Disease/ Diagnostics
7	Expression
19	General Information
4	General Stability
127	Inhibitors
8	kcat/KM [mM/s]
39	Ki Value [mM]
85	KM Value [mM]
10	Localization
2	Metals/Ions
29	Molecular Weight [Da]
41	Natural Substrates/ Products (Substrates)
667	Organism
8	Pathway
483	PDB ID
23	pH Optimum
7	pH Range
1	pH Stability
78	Protein Variants
46	Purification (Commentary)
18	Reaction
3	Reaction Type
127	Reference
1	Renatured (Commentary)
86	Source Tissue
20	Specific Activity [micromol/min/mg]
6	Storage Stability
200	Substrates and Products (Substrate)
35	Subunits
81	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
1	Temperature Range [°C]
8	Temperature Stability [°C]
6	Turnover Number [1/s]

KM Value

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KM Value on EC 2.4.2.3 - uridine phosphorylase

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0.121 - 0.13

2'-deoxyuridine

2 entries

0.756

5'-deoxy-5-fluorouridine

Mus musculus

638543

0.1

5-bromodeoxyuridine

Haemophilus influenzae

638532

0.03

5-Bromouridine

Haemophilus influenzae

638532

0.427

5-fluoro-2'-deoxyuridine

Homo sapiens

O95045

pH 7.4, 37°C

657743

0.036 - 0.06

5-fluorouracil

3 entries

0.024

5-fluorouridine

Homo sapiens

O95045

pH 7.4, 37°C

657743

0.065 - 4

5-methyluridine

4 entries

0.02 - 0.087

alpha-D-ribose-1-phosphate

5 entries

0.3 - 0.71

deoxyuridine

2 entries

0.005

Inosine

Plasmodium falciparum

Q8I3X4

pH 7.5, 25°C

722185

0.076 - 16.1

phosphate

12 entries

0.017 - 0.14

ribose 1-phosphate

5 entries

0.0489 - 0.215

thymidine

5 entries

0.06 - 0.485

Uracil

7 entries

0.016 - 7.55

uridine

25 entries

additional information

14 entries