Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.4.2.28: S-methyl-5'-thioadenosine phosphorylase

This is an abbreviated version!
For detailed information about S-methyl-5'-thioadenosine phosphorylase, go to the full flat file.

Word Map on EC 2.4.2.28

Reaction

S-methyl-5'-thioadenosine
+
phosphate
=
adenine
 +
S-methyl-5-thio-alpha-D-ribose 1-phosphate

Synonyms

5'-deoxy-5'-methylthioadenosine phosphorylase, 5'-deoxy-5'-methylthioadenosine phosphorylase II, 5'-deoxy-5'-methylthioadenosine:orthophosphate methylthioribosyltransferase, 5'-methylthioadenosine nucleosidase, 5'-methylthioadenosine phosphorylase, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, 5-methylthioadenosine phosphorylase, 5’-methylthioadenosine phosphorylase, MeSAdo phosphorylase, MeSAdo/Ado phosphorylase, methylthioadenosine nucleosidase, methylthioadenosine nucleoside phosphorylase, methylthioadenosine phosphorylase, MTA phosphorylase, MTAN, MTAN1, MTAN2, MTAP, Mtap protein, MTAPase, MTN1, MTN2, PfMTAP, phosphorylase, methylthioadenosine, RSFP, Rv0535, SsMTAP, SsMTAP II, SsMTAPII, SSO2343

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.28 S-methyl-5'-thioadenosine phosphorylase

Source Tissue

Source Tissue on EC 2.4.2.28 - S-methyl-5'-thioadenosine phosphorylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
MTAP is not detectable in 39% of chordomas
Manually annotated by BRENDA team
-
diffuse histiocytic lymphoma cell line, possesses no enzyme activity, but intact gene
Manually annotated by BRENDA team
highest level
Manually annotated by BRENDA team
-
and progenitor cells
Manually annotated by BRENDA team
-
high expression in activated hepatic stellate cells
Manually annotated by BRENDA team
-
cell line derived from metastases of malignant melanomas
Manually annotated by BRENDA team
-
tumor-derived cell line, bladder carcinoma
Manually annotated by BRENDA team
-
peripheral blood
Manually annotated by BRENDA team
-
diffuse, histiocytic
Manually annotated by BRENDA team
-
cell line derived from primary cutaneous melanoma
Manually annotated by BRENDA team
-
cell line derived from metastases of malignant melanomas
Manually annotated by BRENDA team
-
cell line derived from metastases of malignant melanomas
Manually annotated by BRENDA team
-
cell line derived from primary cutaneous melanoma
Manually annotated by BRENDA team
-
primary
Manually annotated by BRENDA team
-
SK-Ml-28 cell line derived from metastases of malignant melanomas
Manually annotated by BRENDA team
-
lung fibroblast cell line
Manually annotated by BRENDA team
-
decreased or no expression
Manually annotated by BRENDA team
-
CD34+ erythroid burst-forming unit, granulocyte/monocyte colony-forming unit, granulocyte/erythrocyte/macrophage/megakaryocyte colony-forming unit progenitors and primitive high proliferative potential colony-forming cells in the purified CD34+ cells are cultured
Manually annotated by BRENDA team
-
tumor-derived cell line, Burkitt's lymphoma
Manually annotated by BRENDA team
-
tumor-derived cell line, neuroblastoma
Manually annotated by BRENDA team
-
FC1010 skin fibroblast cell line
Manually annotated by BRENDA team
additional information